3,5-Bis(trifluoromethyl)phenylacetic acid CAS 85068-33-3
| CAS No. | 85068-33-3 |
| Molecular Formula | C10H6F6O2 |
| Molecular Weight | 272.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3,5-Bis(trifluoromethyl)phenylacetic acid.
CATO supplies 3,5-Bis(trifluoromethyl)phenylacetic acid (CAS 85068-33-3), a certified reference material (molecular formula C10H6F6O2, MW 272.14 g/mol) for analytical method development and quality control.
Structurally, 3,5-Bis(trifluoromethyl)phenylacetic acid (C10H6F6O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 272.14 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3,5-Bis(trifluoromethyl)phenylacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6F6O2 |
| Molecular Weight | 272.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
Related Bis Standards
- 2,4-Bis(trifluoromethyl)phenylacetic Acid (CAS 177952-39-5)
- 3,5-Bis(trifluoromethyl)-2-methoxybenzaldehyde (CAS 197015-73-9)
- 2-[2,5-bis(trifluoromethyl)phenyl]acetic acid (CAS 302912-02-3)
- 3’,5’-Bis(trifluoromethyl)-2-hydroxyacetophenone (CAS 944277-15-0)
- 3,5-Bis(trifluoromethyl)benzamidoxime (CAS 72111-09-2)
- 3,5-Bis(trifluoromethyl)benzohydrazide (CAS 26107-82-4)
- 2,5-Bis(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(1H)-one (CAS 198953-52-5)
- 4,6-Bis(trifluoromethyl)-1,2-dihydro-2-thioxopyridine-3-carbonitrile (CAS 265665-03-0)
Recommended Standards
- 497863-61-3 N-[(3-Bromophenyl)methylene]-2,2-dimethoxy-ethanamine N-[(3-Bromophenyl)methylene]-2,2-dimethoxyethanamine (CAS 497863-61-3)
- Valsartan Impurity 10 (CAS 114772-54-2)
- tert-Butyl 6-(bromomethyl)nicotinate (CAS 912550-19-7)
- Valsartan Impurity 96 (CAS CATO-C4X-105796)
- 4-Chlorospiro[indoline-3,4'-piperidin]-2-one hydrochloride (CAS 1713163-31-5)
- Ethyl 6-methyl-2-(methylthio)pyrimidine-4-carboxylate (CAS 1644431-48-0)
- 8-Bromo-2,3-dihydrobenzo[b][1,4]dioxine-6-carbothioamide (CAS 1094225-91-8)
- 3-(Thiophen-2-yl)-N-[4-(trifluoromethoxy)phenyl]-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide (CAS 477845-16-2)
- 2-(4-Azaspiro[2.4]heptan-4-yl)ethan-1-amine (CAS 2045189-57-7)
- 1,3-Difluoro-2-(5-fluoro-2-methoxyphenoxy)-5-(trifluoromethyl)benzene (CAS 2244087-05-4)
- 2,3-Dimethylindole-5-carbaldehyde (CAS 66258-21-7)
- 2-(5-Benzyl-4H-1,2,4-triazol-3-yl)acetic acid hydrochloride (CAS 1187927-29-2)
- tert-Butyl ((1-((S)-2-amino-3-methylbutanoyl)piperidin-3-yl)methyl)(cyclopropyl)carbamate (CAS 1354029-23-4)
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
Why CATO?
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