4-Fluoro-2-(trifluoromethyl)-1H-indole CAS 1780932-13-9
| CAS No. | 1780932-13-9 |
| Molecular Formula | C9H5F4N |
| Molecular Weight | 203.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Fluoro-2-(trifluoromethyl)-1H-indole.
CATO supplies 4-Fluoro-2-(trifluoromethyl)-1H-indole (CAS 1780932-13-9), a certified reference material (molecular formula C9H5F4N, MW 203.14 g/mol) for analytical method development and quality control.
The molecular framework of 4-Fluoro-2-(trifluoromethyl)-1H-indole (C9H5F4N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Fluoro-2-(trifluoromethyl)-1H-indole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5F4N |
| Molecular Weight | 203.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 2-(3-Fluoro-2-(trifluoromethyl)phenyl)acetonitrile (CAS 1000526-58-8)
- 5-Fluoro-2-(trifluoromethyl)-1H-indole (CAS 1007235-33-7)
- 7-Fluoro-4-(trifluoromethyl)-1h-indole (CAS 1167055-51-7)
- 2-Fluoro-5-methyl-4-(trifluoromethyl)benzonitrile (CAS 1323966-20-6)
- 4-Fluoro-3-methyl-5-(trifluoromethyl)benzonitrile (CAS 1373920-92-3)
- 7-Fluoro-5-(trifluoromethyl)-1H-indole (CAS 1493799-75-9)
- 7-Fluoro-2-(trifluoromethyl)-1H-indole (CAS 1783734-91-7)
- 2-(2-Fluoro-6-(trifluoromethyl)phenyl)acetonitrile (CAS 179946-34-0)
Recommended Standards
- Methyl 2-(difluoromethyl)-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 1774901-13-1)
- 2-cyclopropyl-4-(difluoromethyl)-1,3-oxazole-5-carboxylic acid (CAS 1698970-59-0)
- 2,2-Difluoro-2-(3-methoxypyridin-2-yl)acetic acid (CAS 1698403-23-4)
- 1,4-Difluoro-2-ethoxy-6-nitrobenzene (CAS 1803790-26-2)
- 3-Amino-1,1,1-trifluoro-4-phenylbutan-2-ol (CAS 124044-49-1)
- Hexahydropyridazine hydrochloride (CAS 89990-53-4)
- Methyl 1,3-dibenzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 1335055-96-3)
- Ethyl 4-Bromo-3,5-difluorobenzoate (CAS 1562995-70-3)
- 3,4,7-Trimethyl-1-benzofuran-2-carboxylic acid (CAS 53715-96-1)
- 1-(2,2-Diethoxyethyl)piperidin-4-ol (CAS 91249-91-1)
- Benazepril EP Impurity B(Mixture of Enantiomers) (CAS 88372-39-8)
- Isopropyl(phenyl)phosphinic acid (CAS 16543-43-4)
- 6-Bromo-5-(difluoromethyl)-4-methoxynicotinaldehyde (CAS 1805428-48-1)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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