4,6-Dibromoquinazoline CAS 1781044-15-2
| CAS No. | 1781044-15-2 |
| Molecular Formula | C8H4Br2N2 |
| Molecular Weight | 287.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,6-Dibromoquinazoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,6-Dibromoquinazoline (CAS 1781044-15-2), a certified reference material (molecular formula C8H4Br2N2, MW 287.94 g/mol) for analytical method development and quality control.
The molecular framework of 4,6-Dibromoquinazoline (C8H4Br2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4Br2N2 |
| Molecular Weight | 287.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Dibromoquinazoline Standards
Recommended Standards
- 2,6-Dibromoquinoxaline (CAS 175858-10-3)
- 3,8-Dibromo-1,6-naphthyridine (CAS 17965-75-2)
- 5,7-Dibromoquinoxaline (CAS 1644115-99-0)
- 3,5-Dibromo-1,7-naphthyridine (CAS 17965-77-4)
- (S)-4-((1-(3,5-bis(trifluoromethyl)phenyl)-1H-indol-3-yl)methyl)-2,5,5-trimethyl-4,5-dihydrooxazole (CAS 2195357-79-8)
- (2-Chloro-5-methoxyphenyl)hydrazine (CAS 69833-19-8)
- (E)-3-(2-Chlorophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (CAS 204974-26-5)
- 1,4-di-tert-butyl 2-methylpiperazine-1,4-dicarboxylate (CAS 959417-67-5)
- Tert-butyl 7-bromo-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate (CAS 1375301-99-7)
- (1S,5S,6S)-3-azabicyclo[3.2.1]octan-6-ol (CAS 1932778-13-6)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,4-difluorophenyl)methanone (CAS 898762-34-0)
- 3-(Methylsulfinyl)-1H-indole (CAS 86925-06-6)
- N'-(2-bromo-6-fluorobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 2082699-12-3)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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