Ipratropium Impurity 24 (Mixture of Isomers) CAS 17812-46-3

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.17812-46-3
Molecular FormulaC20H28NO2
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ipratropium Impurity 24 (Mixture of Isomers) CAS 17812-46-3 chemical structure

Description

The occurrence of Ipratropium Impurity 24 (Mixture of Isomers) is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Ipratropium Impurity 24 (Mixture of Isomers) (CAS 17812-46-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H28NO2Br and a molecular weight of 394.35 g/mol.

Structurally, Ipratropium Impurity 24 (Mixture of Isomers) (C20H28NO2Br) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 394.35 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ipratropium Impurity 24 (Mixture of Isomers) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H28NO2 Br
Molecular Weight394.35 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Halogen ContentBr-containing
Nitrogen Atoms1

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