Ibrutinib Impurity 11 CAS 2031255-27-1
| CAS No. | 2031255-27-1 |
| Molecular Formula | C28H26N6O3 |
| Molecular Weight | 494.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ibrutinib Impurity 11.
As a process- or degradation-related impurity, Ibrutinib Impurity 11 (CAS 2031255-27-1, C28H26N6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ibrutinib Impurity 11 (C28H26N6O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 494.54 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ibrutinib Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H26N6O3 |
| Molecular Weight | 494.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 6 |
Related Ibrutinib Standards
- Ibrutinib Impurity 108 (CAS CATO-C4X-1064108)
- Ibrutinib Impurity 19 (CAS 1917333-91-5)
- Ibrutinib Impurity 126 (CAS 2190506-55-7)
- Ibrutinib Impurity 139 (CAS CATO-C4X-1064139)
- Ibrutinib Impurity 128 (CAS 2190506-56-8)
- Ibrutinib Impurity 133 (CAS CATO-C4X-1064133)
- Ibrutinib Impurity 191 (CAS CATO-C4X-1064191)
- Ibrutinib Impurity 177 (CAS CATO-C4X-1064177)
Recommended Standards
- trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate (CAS 57405-08-0)
- Rivaroxaban Impurity 86 (CAS CATO-C4X-109086)
- H-Glu-Ser-Leu-Phe-OH (H-1212.0050) (CAS 286471-35-0)
- Cilnidipine Impurity 1 (CAS CATO-C4X-17961)
- Fexofenadine Impurity 35 (CAS CATO-C4X-179435)
- Cefonicid Impurity 2 (CAS CATO-C4X-23043)
- Bosentan impurity 17 (CAS CATO-C4X-156417)
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- 1-(3-Methoxyisothiazol-5-yl)ethan-1-amine (CAS 1935024-09-1)
- 2-Chloro-1-(4-methylfuran-2-yl)ethanone (CAS 133674-52-9)
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- 2-((2-Chlorobenzyl)amino)-1,1-bis(4-fluorophenyl)ethan-1-ol hydrochloride (CAS 317822-06-3)
- 2-(4-Undecylcyclohexyl)acetic acid (CAS 320423-74-3)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com