Tert-butyl 3-(aminomethyl)-3-(trifluoromethyl)azetidine-1-carboxylate CAS 1781345-39-8
| CAS No. | 1781345-39-8 |
| Molecular Formula | C10H17F3N2O2 |
| Molecular Weight | 254.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Tert-butyl 3-(aminomethyl)-3-(trifluoromethyl)azetidine-1-carboxylate (CAS 1781345-39-8), a certified reference material (molecular formula C10H17F3N2O2, MW 254.25 g/mol) for analytical method development and quality control.
Structurally, Tert-butyl 3-(aminomethyl)-3-(trifluoromethyl)azetidine-1-carboxylate (C10H17F3N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 254.25 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17F3N2O2 |
| Molecular Weight | 254.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-[2-(trifluoromethyl)pyrrolidin-2-yl]-1H-indole (CAS 1774374-53-6)
- 2-(Piperidin-1-yl)-6-(trifluoromethyl)benzonitrile (CAS 1795660-79-5)
- tert-Butyl (4-(trifluoromethyl)pyrrolidin-3-yl)carbamate (CAS 168545-06-0)
- H-Lys(Boc)-OH-<SUP>13</SUP>C<SUB>6</SUB>,<SUP>15</SUP>N<SUB>2</SUB> (CAS 1809716-82-2)
- 5-(1,3-Dioxolan-2-yl)-2-thienyl methyl ketone (CAS 773097-36-2)
- 3-bromo-2-fluoro-N,N-dimethylbenzamide (CAS 1231891-86-3)
- 1-(2,3-Dichlorophenyl)cyclopentanemethanamine (CAS 2091962-70-6)
- Triethyl O-Acetylcitrate (CAS 77-89-4)
- 4-(Morpholine-4-carboxamido)benzoic acid (CAS 163587-59-5)
- 3-ethylbenzene-1-sulfonyl chloride (CAS 34586-44-2)
- 2,4-Diamino-3-Fluoro-4-Oxobutanoic Acid (CAS 72016-54-7)
- 3-((3,5-Dimethylphenoxy)methyl)benzoic acid (CAS 938140-74-0)
- Lycoctonine (CAS 26000-17-9)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com