4,4-Difluoro-1-methylpyrrolidin-3-ol CAS 1781347-63-4
| CAS No. | 1781347-63-4 |
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,4-Difluoro-1-methylpyrrolidin-3-ol.
CATO supplies 4,4-Difluoro-1-methylpyrrolidin-3-ol (CAS 1781347-63-4), a certified reference material (molecular formula C5H9F2NO, MW 137.13 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4,4-Difluoro-1-methylpyrrolidin-3-ol is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 137.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4,4-Difluoro-1-methylpyrrolidin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 6,6-difluoro-1,4-oxazepane (CAS 1273565-78-8)
- 3,3-Difluoro-4-methoxy-pyrrolidine (CAS 1638920-22-5)
- 2,2-difluoro-2-(oxetan-3-yl)ethan-1-amine (CAS 1783697-93-7)
- 3,3-Difluoro-4-hydroxypyrrolidin-2-one (CAS 1914929-27-3)
- 4,4-Difluoro-3-methyl-1,3-oxazolidin-2-one (CAS 701231-95-0)
- 4,5-Difluoro-3-methyl-1,3-oxazolidin-2-one (CAS 701231-96-1)
- Methyl 3,3-difluoro-2-oxopropanoate (CAS 139704-68-0)
- 4,4-Difluoro-2-methylbutanoic acid (CAS 1010422-68-0)
Recommended Standards
- [3-(Difluoromethyl)oxetan-3-yl]methanamine (CAS 1781121-31-0)
- (4,4-difluorooxolan-3-yl)methanamine (CAS 1780993-10-3)
- 2-(Azetidin-3-yl)-2,2-difluoroethan-1-ol (CAS 1783698-04-3)
- 1-((Difluoromethoxy)methyl)cyclopropan-1-amine (CAS 1780531-13-6)
- 4-(Diethylamino)benzimidamide (CAS 1019529-61-3)
- 4-(3-Aminophenoxy)benzonitrile (CAS 30202-93-8)
- Z-Tyr-OBzl (CAS 5513-40-6)
- 3-((4-Methylcyclohexyl)amino)propan-1-ol (CAS 1042611-38-0)
- 3-((tert-Butoxycarbonyl)(methyl)amino)-2-(3-methylbenzyl)propanoic acid (CAS 886364-81-4)
- Benzyl 3-(((2-hydroxyethyl)thio)methyl)piperidine-1-carboxylate (CAS 1353945-68-2)
- 6-(Trans-5-methyl-2-oxoimidazolidin-4-yl)hexanoic acid (CAS 34879-36-2)
- Z-His(Boc)-OH (CAS 32675-94-8)
- 4-METHYL VALERYL PIPERIDINE THIOAMIDE (CAS 289677-13-0)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com