1-(difluoromethyl)cyclobutane-1-carbaldehyde CAS 1781544-23-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1781544-23-7
Molecular FormulaC6H8F2O
Molecular Weight134.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(difluoromethyl)cyclobutane-1-carbaldehyde CAS 1781544-23-7 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

1-(difluoromethyl)cyclobutane-1-carbaldehyde (CAS 1781544-23-7) is a high-purity analytical reference standard with the molecular formula C6H8F2O and a molecular weight of 134.12 g/mol.

The molecular framework of 1-(difluoromethyl)cyclobutane-1-carbaldehyde (C6H8F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), 1-(difluoromethyl)cyclobutane-1-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H8F2O
Molecular Weight134.12 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1994
Halogen ContentF-containing

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