(S)-7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-8-(trifluoromethoxy)-1,4-dihydroquinoline-3-carboxylic acid CAS 178174-20-4
| CAS No. | 178174-20-4 |
| Molecular Formula | C18H17F4N3O4 |
| Molecular Weight | 415.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (S)-7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-8-(trifluoromethoxy)-1,4-dihydroquinoline-3-carboxylic acid (CAS 178174-20-4), a certified reference material (molecular formula C18H17F4N3O4, MW 415.34 g/mol) for analytical method development and quality control.
The molecular framework of (S)-7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-8-(trifluoromethoxy)-1,4-dihydroquinoline-3-carboxylic acid (C18H17F4N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (S)-7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-8-(trifluoromethoxy)-1,4-dihydroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17F4N3O4 |
| Molecular Weight | 415.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related S Standards
- (S)-7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-8-(difluoromethoxy)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 178174-19-1)
- 7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 105859-20-9)
- 7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-8-ethoxy-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182868-77-5)
- (S)-7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-5-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 178233-18-6)
- (S)-7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 133298-78-9)
- 7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 99734-98-2)
- 7-(3-Aminopyrrolidin-1-yl-1-Tert-Butyl-6-Fluoro-4-Oxo-1,8-Naphthyridine-3-Carboxylic Acid (CAS 116163-01-0)
- (S)-7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 178174-16-8)
Recommended Standards
- 4-(3-Bromophenyl)-6-phenyldibenzo[b,d]thiophene (CAS 1616092-81-9)
- 2-((2,6-Dichlorophenyl)thio)-N'-(diphenylmethylene)acetohydrazide (CAS 341968-01-2)
- 3-(Furan-2-yl)-5-(1-((4-(trifluoromethoxy)phenyl)sulfonyl)azetidin-3-yl)-1,2,4-oxadiazole (CAS 1428374-57-5)
- Sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-((3-methylbut-3-en-1-yl)amino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl phosphate (CAS 20268-93-3)
- Benodanil Impurity 3 (CAS 501352-80-3)
- Methyl 6-(4-cyanophenyl)pyridine-2-carboxylate (CAS 1820607-47-3)
- ((4-Methoxyphenyl)sulfonyl)histidine (CAS 1007971-46-1)
- Pyrrolidin-3-ylmethyl trifluoromethanesulfonate (CAS 1337880-78-0)
- Tofacitinib Impurity N33 (CAS 1615709-90-4)
- n-Cyclopropyl-4-formylbenzamide (CAS 550363-79-6)
- 6-Oxo-6H-[1,3]dioxolo[4,5-g]chromene-7-carboxylic acid (CAS 84632-14-4)
- 2-((1-Isopropyl-1H-pyrazol-5-yl)amino)benzoic acid (CAS 183151-32-8)
- 4-{[(4-chlorophenyl)methyl]sulfanyl}-6-(methoxymethyl)-2-methylpyrimidine (CAS 338747-83-4)
- Autocamtide-2-Related Inhibitory Peptide TFA (CAS 167114-91-2（free base）)
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