3-(Hydroxymethyl)azetidin-2-one CAS 1781802-55-8
| CAS No. | 1781802-55-8 |
| Molecular Formula | C4H7NO2 |
| Molecular Weight | 101.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 101.10 g/mol gives 3-(Hydroxymethyl)azetidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(Hydroxymethyl)azetidin-2-one (CAS 1781802-55-8), molecular formula C4H7NO2 and molecular weight 101.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Hydroxymethyl)azetidin-2-one (C4H7NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(Hydroxymethyl)azetidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H7NO2 |
| Molecular Weight | 101.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 1 |
Related Hydroxymethyl Standards
- (R)-4-(hydroxymethyl)azetidin-2-one (CAS 91815-14-4)
- (S)-4-(hydroxymethyl)azetidin-2-one (CAS 72776-07-9)
- 4-(Hydroxymethyl)azetidin-2-one (CAS 74694-48-7)
- N-(Hydroxymethyl)acrylamide (CAS 924-42-5)
- (R)-3-(Hydroxymethyl)pyrrolidine (CAS 110013-18-8)
- 3-(hydroxymethyl)cyclobutan-1-one (CAS 183616-18-4)
- 2-(hydroxymethyl)cyclobutan-1-one (CAS 23107-52-0)
- 3-(Hydroxymethyl)but-3-en-2-one (CAS 73255-29-5)
Recommended Standards
- 4-Aminodihydrofuran-2(3H)-one (CAS 16504-58-8)
- (1S,2R)-2-Aminocyclopropane-1-carboxylic acid (CAS 1932028-98-2)
- 1,2-oxazole-5-carbaldehyde (CAS 16401-14-2)
- (4,5-Dihydrooxazol-2-yl)methanol (CAS 22375-00-4)
- 1-(3'-Chlorosulfonyl-4'-methoxyphenyl)-1-propanone-methyl-d3 1189984-41-5 (CAS 1189984-41-5)
- (2-Chloro-6-fluorophenyl)boronic acid (CAS 313545-32-3)
- 6-(Trifluoromethyl)-1H,2H,3H-pyrrolo[3,4-c]pyridine (CAS 905275-83-4)
- [1-(2-amino-6-chloropyrimidin-4-yl)pyrrolidin-2-yl]methanol (CAS 1494756-17-0)
- D-(+)-Raffinose undecaacetate (CAS 6424-12-0)
- (6-methyl-1H-1,3-benzodiazol-2-yl)(phenyl)methanamine (CAS 1092265-94-5)
- 4-Iodo-3-phenylisoquinoline (CAS 312612-62-7)
- (4-((8-Bromooctyl)oxy)-2-hydroxyphenyl)(4-chlorophenyl)methanone (CAS 945663-27-4)
- Hydrazinecarboxylic acid 2-trimethylsilanyl-ethyl ester (CAS 154876-20-7)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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