8-bromo-2-chloro-pyrido[4,3-d]pyrimidine CAS 1782598-52-0
| CAS No. | 1782598-52-0 |
| Molecular Formula | C7H3BrClN3 |
| Molecular Weight | 244.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-bromo-2-chloro-pyrido[4,3-d]pyrimidine is closely related to a nitrile group, chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-bromo-2-chloro-pyrido[4,3-d]pyrimidine (CAS 1782598-52-0), molecular formula C7H3BrClN3 and molecular weight 244.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-bromo-2-chloro-pyrido[4,3-d]pyrimidine (C7H3BrClN3) is characterized by a nitrile group, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-bromo-2-chloro-pyrido[4,3-d]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3BrClN3 |
| Molecular Weight | 244.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related bromo Standards
- 6-Bromo-4-chloropyrido[2,3-d]pyrimidine (CAS 1215787-31-7)
- 7-Bromo-2-chloropyrido[3,2-d]pyrimidine (CAS 1234615-87-2)
- 7-bromo-3-chloro-pyrido[2,3-b]pyrazine (CAS 1240594-95-9)
- 8-Bromo-4-chloropyrido[4,3-d]pyrimidine (CAS 1269421-61-5)
- 8-Bromo-5-chloropyrido[4,3-d]pyrimidine (CAS 1352926-12-5)
- 7-Bromo-4-chloropyrido[2,3-d]pyrimidine (CAS 1379348-17-0)
- 3-Bromo-6-chloropyrido[2,3-b]pyrazine (CAS 1431873-00-5)
- 8-Bromo-5-chloropyrido[3,4-b]pyrazine (CAS 1590409-71-4)
Recommended Standards
- 7-Bromo-6-chloropyrido[2,3-b]pyrazine (CAS 1823374-98-6)
- 6-Bromo-4-chloropyrido[3,4-d]pyrimidine (CAS 1824048-52-3)
- 7-Bromo-8-chloropyrido[2,3-b]pyrazine (CAS 1936396-72-3)
- (3-Chloro-4-(2-ethoxyethoxy)phenyl)boronic acid (CAS 279261-91-5)
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