1,4-Dichlorophthalazine-6-carbonitrile CAS 178308-61-7
| CAS No. | 178308-61-7 |
| Molecular Formula | C9H3Cl2N3 |
| Molecular Weight | 224.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 224.05 g/mol gives 1,4-Dichlorophthalazine-6-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1,4-Dichlorophthalazine-6-carbonitrile (CAS 178308-61-7), molecular formula C9H3Cl2N3 and molecular weight 224.05 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 1,4-Dichlorophthalazine-6-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 224.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H3Cl2N3 |
| Molecular Weight | 224.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichlorophthalazine Standards
- 1,4-Dichlorophthalazine-6-carbaldehyde (CAS 1416713-31-9)
- 6,7-Dichlorophthalazine-5,8-dione (CAS 102072-85-5)
- 1,4-Dichlorophthalazine-6-carboxylic acid (CAS 182620-31-1)
- 1,6-Dichlorophthalazine (CAS 124556-78-1)
- 1,8-dichlorophthalazine (CAS 1263378-72-8)
- 1,7-Dichlorophthalazine, 97% (CAS 873967-47-6)
- Methyl 1,4-dichlorophthalazine-6-carboxylate (CAS 1416713-80-8)
- 1,4-Dichlorophthalazine-6-carbonyl chloride (CAS 2380-50-9)
Recommended Standards
- 5-Bromo-4-phenyl-1,2-oxazole (CAS 1781624-27-8)
- 4-Bromoisoquinolin-7-ol (CAS 1783631-45-7)
- 2-(4-Bromophenyl)-1,3-oxazole (CAS 176961-50-5)
- 4-Bromoisoquinolin-8-ol (CAS 1784957-23-8)
- Phenylmethyl N-(acetyloxy)carbamate (CAS 180798-01-0)
- (S)-2-Amino-N-(3-fluorobenzyl)-N-isopropylpropanamide (CAS 1354000-33-1)
- 3,6-Dimethylpyrimidine-2,4(1H,3H)-dione (CAS 19674-60-3)
- Losartan Impurity 1 (CAS 79047-41-9)
- 3-(m-Tolyl)pyridin-4-amine (CAS 1339667-18-3)
- 1-(1,1-Difluoroethyl)-2-nitrobenzene (CAS 57554-57-1)
- 2-(4-(((9H-fluoren-9-yl)methoxy)carbonyl)-2-oxopiperazin-1-yl)acetic acid (CAS 738625-30-4)
- Resorcin Monoacetate (CAS 102-29-4)
- 4-Difluoromethoxy-3-(trifluoromethyl)pyridine (CAS 1803825-89-9)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
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