6-Bromo-4-ethoxy-2,3-difluorophenol CAS 1783559-46-5
| CAS No. | 1783559-46-5 |
| Molecular Formula | C8H7BrF2O2 |
| Molecular Weight | 253.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 6-Bromo-4-ethoxy-2,3-difluorophenol (CAS 1783559-46-5), a certified reference material (molecular formula C8H7BrF2O2, MW 253.04 g/mol) for analytical method development and quality control.
The molecular framework of 6-Bromo-4-ethoxy-2,3-difluorophenol (C8H7BrF2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7BrF2O2 |
| Molecular Weight | 253.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-1-(difluoromethoxy)-2-methoxybenzene (CAS 1095544-42-5)
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Recommended Standards
- (5-Bromo-2,3-difluoro-4-methoxyphenyl)methanol (CAS 1781546-49-3)
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- 1-Bromo-3,5-difluoro-2-(methoxymethoxy)benzene (CAS 1803589-44-7)
- (4,5-Dihydro-1H-pyrrol-3-yl)boronic acid (CAS 2855269-02-0)
- 2,4-Dichloro-3-methylaniline (CAS 19853-79-3)
- (4-Bromothiophen-3-yl)(piperidin-1-yl)methanone (CAS 2022184-92-3)
- 4-(2'-Fluoro-[1,1'-biphenyl]-4-yl)-N-(4-hydroxyphenyl)butanamide (CAS 41179-33-3)
- 1-ethyl-2-(pyrrolidin-2-yl)-1H-1,3-benzodiazole (CAS 1152522-12-7)
- 1-(2-Fluoro-5-iodophenyl)ethan-1-one (CAS 1159512-66-9)
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