5-Chloro-3'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol CAS 178374-37-3
| CAS No. | 178374-37-3 |
| Molecular Formula | C13H8ClF3O |
| Molecular Weight | 272.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-3'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol (CAS 178374-37-3), molecular formula C13H8ClF3O and molecular weight 272.65 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H8ClF3O, 5-Chloro-3'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 272.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-3'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8ClF3O |
| Molecular Weight | 272.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-N-phenyl-5-(trifluoromethyl)-2-pyridinamine (CAS 1163681-50-2)
- 4-Chloro-6-methyl-2-(4-(trifluoromethyl)phenyl)pyrimidine (CAS 125904-05-4)
- 4-Chloro-2'-(trifluoromethyl)-[1,1'-biphenyl]-3-ol (CAS 1261846-60-9)
- 4-Chloro-3-hydroxy-3'-(trifluoromethyl)biphenyl (CAS 1261857-41-3)
- 3-Chloro-6-(m-tolyl)-4-(trifluoromethyl)pyridazine (CAS 1271475-10-5)
- 3-Chloro-6-(p-tolyl)-4-(trifluoromethyl)pyridazine (CAS 1271475-96-7)
- 6-CHLORO-3-(ETHOXYCARBONYL)-1,8A-DIHYDRO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE-8-CARBOXYLIC ACID (CAS 1447606-93-0)
- 2-((7-Chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)(methyl)amino)ethan-1-ol (CAS 376370-18-2)
Recommended Standards
- 1-(4-Chlorophenoxy)-2-(difluoromethyl)-3-fluorobenzene (CAS 2149602-13-9)
- 3-((7-Chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)propan-1-ol (CAS 372975-34-3)
- 3-(Difluoromethoxy)-4-methoxybenzenesulfonyl chloride (CAS 929341-67-3)
- 4-[2-Chloro-5-(trifluoromethyl)phenyl]phenol (CAS 634192-46-4)
- 2-Benzoylthiophene (CAS 135-00-2)
- 2-(Pyridin-2-yl)-2H-[1,3]dioxolo[4,5-f]indazole (CAS 1352305-23-7)
- Methyl 2-(2-chloroacetamido)acetate (CAS 76969-81-8)
- 4-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)butanoic acid (CAS 2413732-05-3)
- 1-(4-(Dimethylamino)phenyl)propan-1-one (CAS 26672-58-2)
- Methyl 5-(o-Tolyl)isoxazole-3-carboxylate (CAS 668970-81-8)
- 7-Amino-2,3-dichloro-9H-fluoren-9-one (CAS 91821-97-5)
- 2,2-Iminobispropanenitrile (CAS 2869-25-2)
- 1-(3-Isopropylisoxazol-5-yl)ethanol (CAS 301168-22-9)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
Why CATO?
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