methyl 2,2-difluoro-2-(4-piperidyl)acetate CAS 1783742-79-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1783742-79-9
Molecular FormulaC8H13F2NO2
Molecular Weight193.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

methyl 2,2-difluoro-2-(4-piperidyl)acetate CAS 1783742-79-9 chemical structure

Description

The occurrence of methyl 2,2-difluoro-2-(4-piperidyl)acetate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

methyl 2,2-difluoro-2-(4-piperidyl)acetate (CAS 1783742-79-9), molecular formula C8H13F2NO2 and molecular weight 193.19 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, methyl 2,2-difluoro-2-(4-piperidyl)acetate (C8H13F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 193.19 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), methyl 2,2-difluoro-2-(4-piperidyl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H13F2NO2
Molecular Weight193.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1994
Halogen ContentF-containing
Nitrogen Atoms1

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