4-(2,2-Difluoroethyl)piperidine-4-carboxylic acid CAS 1503725-95-8
| CAS No. | 1503725-95-8 |
| Molecular Formula | C8H13F2NO2 |
| Molecular Weight | 193.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(2,2-Difluoroethyl)piperidine-4-carboxylic acid (CAS 1503725-95-8) is a high-purity analytical reference standard with the molecular formula C8H13F2NO2 and a molecular weight of 193.19 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(2,2-Difluoroethyl)piperidine-4-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 193.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H13F2NO2 |
| Molecular Weight | 193.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethyl Standards
- 1-(2,2-Difluoroethyl)piperidine-2-carboxylic acid (CAS 1218200-72-6)
- Methyl 2-[1-(2,2-difluoroethyl)azetidin-3-yl]acetate (CAS 1432678-05-1)
- 1-(2,2-Difluoroethyl)piperidine-3-carboxylic acid (CAS 937602-80-7)
- 1-(2,2-Difluoroethyl)piperidine-4-carboxylic acid (CAS 937602-78-3)
- 4-(1,1-Difluoroethyl)thiazole-2-carboxylic acid (CAS 1780878-51-4)
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- 1-(1,1-Difluoroethyl)naphthalene (CAS 1204295-97-5)
- 2-(1,1-Difluoroethyl)naphthalene (CAS 1204296-00-3)
Recommended Standards
- 2-[(2,2,2-Trifluoroethyl)thio]-pyridine (CAS 162965-54-0)
- Methyl (S)-4,4-difluoro-3,3-dimethylpyrrolidine-2-carboxylate (CAS 1408278-46-5)
- 2-(Methylthio)-3-(trifluoromethyl)pyridine (CAS 1779130-81-2)
- 2-(2,4-Difluorophenyl)-4-methyl-1H-pyrrole (CAS 1351486-83-3)
- 4-(5-Nitroquinolin-6-yl)cyclohexanol (CAS 1150163-86-2)
- 3-Acetyl-2,2-dimethylcyclopropanecarboxylic acid (CAS 111869-21-7)
- 7-Fluoro-3-oxoindane-4-carbonitrile (CAS 1092347-34-6)
- 4-Bromo-6-(difluoromethyl)-2-methoxynicotinaldehyde (CAS 1806870-58-5)
- 5-(Trifluoromethyl)imidazo[1,2-a]pyridin-3-amine (CAS 1780806-70-3)
- 1-(3-(Ethylsulfonyl)propyl)-1h-1,2,4-triazol-3-amine (CAS 1484377-78-7)
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