(3R,4S)-4-(3-fluoro-4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid CAS 1784747-74-5
| CAS No. | 1784747-74-5 |
| Molecular Formula | C12H12FNO4 |
| Molecular Weight | 253.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (3R,4S)-4-(3-fluoro-4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(3R,4S)-4-(3-fluoro-4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1784747-74-5), molecular formula C12H12FNO4 and molecular weight 253.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3R,4S)-4-(3-fluoro-4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid (C12H12FNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H12FNO4 |
| Molecular Weight | 253.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 1-((Benzyloxy)carbonyl)-3-fluoroazetidine-3-carboxylic acid (CAS 1781046-72-7)
- (3R,4S)-4-(2-fluoro-4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1784747-75-6)
- 5-Nitronaphthalene-1-sulfonic acid (CAS 17521-00-5)
- 6-Amino-3-(difluoromethyl)-5-methoxypyridine-2-sulfonamide (CAS 1803685-77-9)
- 4-Amino-3-chloro-5-(trifluoromethyl)benzoic acid (CAS 95656-52-3)
- 2-(Bromomethyl)-5-fluoropyridine (CAS 954225-35-5)
- 3-(3-Bromophenyl)-5-(furan-2-ylmethylene)-4-thioxothiazolidin-2-one (CAS 306322-32-7)
- 7,8-Difluoro-3,4-dihydronaphthalen-2(1H)-one (CAS 675132-40-8)
- 3-{[(4-chlorophenyl)sulfanyl]methyl}-5-phenyl-1,2-oxazole (CAS 478067-78-6)
- 2-(1-Benzofuran-5-yl)-2-methoxyacetic acid (CAS 1554256-85-7)
- Bis(acetoxymethyl) 2,2'-((2-(2-(acetoxymethoxy)-2-oxoethoxy)-4-(6-((acetoxymethoxy)carbonyl)-1H-indol-2-yl)phenyl)azanediyl)diacetate (CAS 130926-94-2)
- N-(5-Bromo-4-methylthiazol-2-yl)acetamide (CAS 21478-95-5)
- (4-(4-Ethoxyphenyl)tetrahydro-2H-pyran-4-yl)methanamine (CAS 1152563-72-8)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
Why CATO?
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