[4-(1,1-Difluoroethyl)oxan-4-yl]methanol CAS 1785196-42-0
| CAS No. | 1785196-42-0 |
| Molecular Formula | C8H14F2O2 |
| Molecular Weight | 180.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
[4-(1,1-Difluoroethyl)oxan-4-yl]methanol (C8H14F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
[4-(1,1-Difluoroethyl)oxan-4-yl]methanol (CAS 1785196-42-0), molecular formula C8H14F2O2 and molecular weight 180.19 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14F2O2 |
| Molecular Weight | 180.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
Related Difluoroethyl Standards
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- 1-(2,2-Difluoroethyl)pyrrolidine-2-carboxylic acid (CAS 1162114-85-3)
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Recommended Standards
- N,N'-Dipropylphosphorodiamidic acid (CAS 1754-59-2)
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- (2-(Difluoromethoxy)cyclohexyl)methanol (CAS 2306278-06-6)
- Ethyl 2,5-dimethyl-3-oxopyrrolidine-1-carboxylate (CAS 90943-02-5)
- Ethyl 2-(bis(benzyloxy)phosphoryl)acetate (CAS 69639-67-4)
- Triundecylamine (CAS 42910-16-7)
- N-([1,1'-Biphenyl]-4-yl)dibenzo[b,d]furan-2-amine (CAS 1300028-94-7)
- N-(3-chlorophenyl)-N-(methylsulfonyl)-L-alanine (CAS 1008026-74-1)
- 2-({4-cyano-1,6-diazatricyclo[6.2.2.0^{2,7}]dodeca-2(7),3,5-trien-5-yl}sulfanyl)-N-(3,5-dichlorophenyl)acetamide (CAS 723748-45-6)
- 2-Bromo-5-(ethylsulfamoyl)benzoic acid (CAS 790271-06-6)
- 6-(Methylamino)-1,2,4-triazine-5-carboxylic acid (CAS 446260-20-4)
- 2-(Aminomethyl)-4-bromo-6-(difluoromethyl)-3-iodopyridine (CAS 1805920-23-3)
- D-[Phe6]-Semaglutide (CAS CATO-C4X-2226213)
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