2-(4,4-Difluoropyrrolidin-3-yl)acetic acid CAS 1785372-29-3
| CAS No. | 1785372-29-3 |
| Molecular Formula | C6H9F2NO2 |
| Molecular Weight | 165.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4,4-Difluoropyrrolidin-3-yl)acetic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(4,4-Difluoropyrrolidin-3-yl)acetic acid (CAS 1785372-29-3), a certified reference material (molecular formula C6H9F2NO2, MW 165.14 g/mol) for analytical method development and quality control.
2-(4,4-Difluoropyrrolidin-3-yl)acetic acid (C6H9F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9F2NO2 |
| Molecular Weight | 165.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoropyrrolidin Standards
- (R)-2-(4,4-Difluoropyrrolidin-2-yl)acetic acid (CAS 1467036-78-7)
- 3-(3,3-Difluoropyrrolidin-1-yl)propan-1-amine (CAS 867007-59-8)
- 2-(3,3-Difluoropyrrolidin-1-yl)ethan-1-ol (CAS 950662-61-0)
- 3-(4,4-Difluoropyrrolidin-2-yl)-5-methyl-1,2,4-oxadiazole (CAS 2097936-51-9)
- 4-(3,3-Difluoropyrrolidin-1-yl)piperidine (CAS 1061682-67-4)
- (1-((3,3-Difluoropyrrolidin-1-yl)methyl)cyclopropyl)methanol (CAS 1892804-98-6)
- (3,3-Difluoropyrrolidin-2-yl)methanol (CAS 1027519-80-7)
- [(2R)-4,4-Difluoropyrrolidin-2-yl]methanol (CAS 1315691-45-2)
Recommended Standards
- 3,8-Difluoroquinoline (CAS 1781159-07-6)
- (3S,4R,5S)-3-fluoro-4-(fluoromethyl)-5-(hydroxymethyl)pyrrolidin-2-one (CAS 1817630-34-4)
- 1-Amino-3,3-difluorocyclopentane-1-carboxylic acid (CAS 1780167-67-0)
- 3-(Difluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1820674-05-2)
- 6-Fluoro-2,3-dihydroquinolin-4(1H)-one (CAS 38470-26-7)
- 4-Methoxy-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1737-27-5)
- Methyl 2,3-dichloroquinoxaline-5-carboxylate (CAS 1643354-85-1)
- 1-(Difluoromethyl)-3-iodopyridin-2(1H)-one (CAS 2092680-07-2)
- 5-Chloro-2-(trifluoromethoxy)benzyl alcohol (CAS 874821-52-0)
- BC-11-38 (CAS 686770-80-9)
- 2-(5-Hexyl-2-styryloxazol-4-yl)acetic acid (CAS 89724-26-5)
- 1-(Boc)-5-Fluoropiperidine-3-carboxylic acid (CAS 1241725-64-3)
- 3-(Pyrrolidin-1-yl)propane-1,2-diol (CAS 85391-19-1)
- 3AEEA-Semaglutide(Endo-AEEA-Semaglutide) (CAS CATO-C4X-2226265)
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