5-(difluoromethyl)pyrazin-2-amine CAS 1785551-80-5
| CAS No. | 1785551-80-5 |
| Molecular Formula | C5H11F2N3 |
| Molecular Weight | 151.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 151.16 g/mol gives 5-(difluoromethyl)pyrazin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(difluoromethyl)pyrazin-2-amine (CAS 1785551-80-5) is a high-purity analytical reference standard with the molecular formula C5H11F2N3 and a molecular weight of 151.16 g/mol.
Structurally, 5-(difluoromethyl)pyrazin-2-amine (C5H11F2N3) contains fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 151.16 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H11F2N3 |
| Molecular Weight | 151.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related difluoromethyl Standards
- 1-[1-(difluoromethyl)-1H-imidazol-2-yl]methanamine (CAS 1094415-91-4)
- 6-(difluoromethyl)pyridazin-3-amine (CAS 1706450-11-4)
- 6-(difluoromethyl)pyridin-3-ol (CAS 1256791-37-3)
- 3-(Difluoromethyl)piperidin-3-ol (CAS 1423026-01-0)
- 4-(Difluoromethyl)piperidin-4-ol (CAS 1423032-03-4)
- 4-(Difluoromethyl)tetrahydro-2H-pyran-4-amine (CAS 1508611-87-7)
- 7-(Difluoromethyl)-1,4-oxazepane (CAS 1780845-60-4)
- 5-(difluoromethyl)-1,3,4-thiadiazol-2-amine (CAS 25306-15-4)
Recommended Standards
- 2-Methylbenzo[d][1,3]dioxol-5-amine (CAS 176735-25-4)
- n-Hydroxy-N-phenylacetamide (CAS 1795-83-1)
- N-hydroxy-2-methylbenzamide (CAS 17512-73-1)
- 2-(2-Methylpyridin-3-yl)acetic acid (CAS 179626-66-5)
- m-PEG2-Tos (CAS 50586-80-6)
- 5-Bromo-2,3-dimethylpyrazine (CAS 111454-68-3)
- 3-(Phenylamino)benzoic Acid (CAS 6025-56-5)
- Molinate-sulfoxide (CAS 52236-29-0)
- 1-Methyl-5-nitro-1H-pyrrole-2-carbonitrile (CAS 2853-30-7)
- 2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide (CAS 2830712-47-3)
- 2-Bromo-1-chloro-4-(trichloromethoxy)benzene (CAS 1417567-88-4)
- (1-((S)-2-((S)-2-Acetamido-3-hydroxypropanamido)propanoyl)pyrrolidin-2-yl)boronic acid (CAS 915283-86-2)
- 6-(1-Methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridine (CAS 1205744-42-8)
- 149471-11-4 Neuropeptide DF2 L-Phenylalaninamide, L-alpha-aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl- Asp-arg-asn-phe-leu-arg-phe-NH2 Aspartyl-arginyl-asparaginyl-phenylalanyl-leucyl-arginyl-phenylalaninamide L-alpha-Aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide DF(2) Neuropeptide Drnflrfamide (CAS 149471-11-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com