1-Methyl-5-nitro-1H-pyrrole-2-carbonitrile CAS 2853-30-7
| CAS No. | 2853-30-7 |
| Molecular Formula | C6H5N3O2 |
| Molecular Weight | 151.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Methyl-5-nitro-1H-pyrrole-2-carbonitrile (CAS 2853-30-7), molecular formula C6H5N3O2 and molecular weight 151.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Methyl-5-nitro-1H-pyrrole-2-carbonitrile (C6H5N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-Methyl-5-nitro-1H-pyrrole-2-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5N3O2 |
| Molecular Weight | 151.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 2-Nitro-1-(prop-2-yn-1-yl)-1H-imidazole (CAS 1070878-68-0)
- 1-Methyl-4-nitro-1h-pyrrole-2-carbonitrile (CAS 89488-02-8)
- 4-Nitro-o-xylene (CAS 99-51-4)
- 1-methyl-6-nitro-4-phenyl-1,4-dihydro-2h-3,1-benzoxazin-2-one 40162-97-8 AR-1C4668 (CAS 40162-97-8)
- 3-Nitro-3-chloromethyloxetane (CAS 1195637-44-5)
- 4-Nitro-1H-pyrazole-1-acetonitrile (CAS 1001500-47-5)
- 2-(3-Nitro-1h-pyrazol-1-yl)acetonitrile (CAS 1006956-03-1)
- 3-Nitro-2-pyridinecarboxaldehyde (CAS 10261-94-6)
Recommended Standards
- 2-(Cyanomethyl)furan-3-carboxylic acid (CAS 59760-39-3)
- 1-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 7465-66-9)
- 2-Amino-5-(2-Furanyl)-1,3,4-oxadiazole (CAS 7659-06-5)
- 1-Hydroxyfuro[3,4-c]pyridin-3(1H)-one (CAS 944900-70-3)
- Lithium pivalate (CAS 14271-99-9)
- 4-Ethylpyridin-3-ol (CAS 83431-03-2)
- Polydextrose (CAS 68424-04-4)
- Fulvestrant impurity 54 (CAS CATO-C4X-191754)
- 1,2-Benzenedicarboxylic acid, polymer with 1,4-benzenedicarboxylic acid and 1,4-butanediol (CAS 68966-59-6)
- 6-(3,5-Dichlorophenyl)-6-oxohexanoic acid (CAS 898765-51-0)
- tert-Butyl 3-(2-chloro-N-isopropylacetamido)pyrrolidine-1-carboxylate (CAS 1353980-45-6)
- Methyl(2-methylpropyl)amine hydrochloride (CAS 89282-62-2)
- Betamethasone Impurity 133 (CAS CATO-C4X-1437133)
- Neuropeptide W-23 (human) (CAS 383415-79-0)
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