Istradefylline Impurity 20 CAS 1785764-26-2
| CAS No. | 1785764-26-2 |
| Molecular Formula | C8H14N4O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Istradefylline Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Istradefylline Impurity 20 (CAS 1785764-26-2, C8H14N4O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Istradefylline Impurity 20 (C8H14N4O2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H14N4O2 HCl |
| Molecular Weight | 234.68 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Istradefylline Standards
- Istradefylline Impurity 13 (CAS 14436-34-1)
- Istradefylline Impurity 22 (CAS 1453190-01-6)
- Istradefylline Impurity 18 (CAS 146946-10-3)
- Istradefylline Impurity 8 (CAS 14773-40-1)
- Istradefylline Impurity 24 (CAS 155270-98-7)
- Istradefylline (CAS 155270-99-8)
- Istradefylline Impurity 19 (CAS 155272-03-0)
- Istradefylline Impurity 3 (CAS 155272-04-1)
Recommended Standards
- Amlodipine Impurity 135 (CAS CATO-C4X-1095135)
- Ticagrelor Impurity 73 D-Tartrate (CAS CATO-C4X-109373)
- Dotinurad Impurity 70 (CAS CATO-C4X-249470)
- 2-Allyl-4,5-dichloropyridazin-3(2H)-one (CAS 77541-70-9)
- 3-Phenyl-5-(phenylmethyl)-2-thioxo-4-imidazolidinone (CAS 4332-97-2)
- 3-(3-Nitrophenyl)-N'-(thiophen-2-ylmethylene)-1H-pyrazole-5-carbohydrazide (CAS 303106-87-8)
- 1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-11-yl)ethan-1-one (CAS 1422065-61-9)
- 2-pyridazin-4-ylacetic acid (CAS 98197-79-6)
- 4-((Methylamino)methyl)-N-phenylpiperidine-1-carboxamide (CAS 1275946-26-3)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com