N-[2-[[2-[(Tetrahydro-2H-pyran-4-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide CAS 1788058-89-8
| CAS No. | 1788058-89-8 |
| Molecular Formula | C19H20F3N5O2 |
| Molecular Weight | 407.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N-[2-[[2-[(Tetrahydro-2H-pyran-4-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide (CAS 1788058-89-8), molecular formula C19H20F3N5O2 and molecular weight 407.39 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-[2-[[2-[(Tetrahydro-2H-pyran-4-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide (C19H20F3N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 407.39 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H20F3N5O2 |
| Molecular Weight | 407.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related N Standards
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Recommended Standards
- (1S,2R)-4-(3-Cyano-5-fluorophenoxy)-2-fluoro-7-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl acetate (CAS 1672668-25-5)
- N,N,N',N',N'',N''-Hexamethyl-1-(1,1,2,2,3,3,6,6,6-nonafluorohexyl)silanetriamine (CAS 186599-46-2)
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- (2E)-1-[4-(1H-1,3-Benzodiazol-1-yl)phenyl]-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-en-1-one (CAS 692287-93-7)
- 3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazole-5-carboxylic acid (CAS 926257-89-8)
- 2-(6-Ethylpyridin-2-yl)ethanamine (CAS 1368342-99-7)
- 2-(2-(4-Ethylcyclohexylidene)hydrazinyl)-2-oxoacetamide (CAS 400054-59-3)
- Atorvastatin Allyl Ester (CAS 915092-85-2)
- 3-[(1-Methylpiperidin-4-yl)oxy]propanenitrile (CAS 98880-85-4)
- 6-Amino-5-nitronicotinic Acid (CAS 89488-06-2)
- 5'-Ethyl-2'-methyl-1h,2'h-[3,3'-bi(1,2,4-triazol)]-5-amine (CAS 1341547-90-7)
- (4S)-3-Acetyl-1,3-thiazolidine-4-carboxylic acid (CAS 104527-63-1)
- 1-Amino-3-(2-isopropylphenoxy)propan-2-ol hydrochloride (CAS 1049784-71-5)
- Dulaglutide (CAS 923950-08-7)
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