4-Chloro-6-fluoroquinoline-3-carboxylic acid CAS 179024-67-0
| CAS No. | 179024-67-0 |
| Molecular Formula | C10H5ClFNO2 |
| Molecular Weight | 225.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-6-fluoroquinoline-3-carboxylic acid (CAS 179024-67-0) is a high-purity analytical reference standard with the molecular formula C10H5ClFNO2 and a molecular weight of 225.60 g/mol.
4-Chloro-6-fluoroquinoline-3-carboxylic acid (C10H5ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-6-fluoroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5ClFNO2 |
| Molecular Weight | 225.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-7-fluoro-3-quinolinecarboxylic acid (CAS 1017157-81-1)
- 2-Chloro-8-fluoroquinoline-3-carboxylic acid (CAS 1017378-95-8)
- 2-Chloro-6-(1-methylhydrazinyl)-4-(trifluoromethyl)pyridine (CAS 1053659-61-2)
- 6-Chloro-N-(1H-tetrazol-5-yl)pyrazine-2-carboxamide (CAS 111374-47-1)
- 7-Chloro-3-fluoroquinoline-8-carboxylic acid (CAS 115813-23-5)
- 5-Chloro-3-(3-fluorophenyl)-1,2-oxazole-4-carbaldehyde (CAS 1188031-85-7)
- 5-Chloro-3-(3-fluorophenyl)isoxazole-4-carbaldehyde (CAS 1188031-90-4)
- 5-Chloro-3-(2-fluorophenyl)-1,2-oxazole-4-carbaldehyde (CAS 1188135-55-8)
Recommended Standards
- 2-(Aminomethyl)-6-chloro-4-(trifluoromethyl)phenol (CAS 1783956-84-2)
- 3-Chloro-4-methyl-5-(trifluoromethoxy)-benzenamine (CAS 1805038-51-0)
- 5-Chloro-2-methyl-4-(trifluoromethoxy)aniline (CAS 1706461-21-3)
- 5-Chloro-2-methoxy-4-(trifluoromethyl)aniline (CAS 1805228-73-2)
- 2-Amino-N,4-dimethyl-N-(thiophen-2-ylmethyl)pentanamide hydrochloride (CAS 1423024-07-0)
- 3-Fluoro-4-(4h-1,2,4-triazol-4-yl)phenol (CAS 1341854-51-0)
- 2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}ethan-1-amine (CAS 160446-03-7)
- 2-Methyl-5-(4-(methylsulfonyl)phenyl)-4-phenylpyridazin-3(2H)-one (CAS 213763-80-5)
- 1-Methyl-3-ethyl-5-[2-(3-(2-carboxyethyl)-benzoxazol-2-ylidene)-ethylidene]-2-thioxo-imidazolidin-4-one (CAS 219556-03-3)
- 3-[(4-Chlorophenyl)[(2-tetrahydropyranyl)oxy]methyl]isoxazole-4-carboxylic Acid (CAS 2006277-13-8)
- 4,5-Difluoro-2-methoxyphenol (CAS 246029-17-4)
- N-(2-aminoethyl)-3-methylfuran-2-carboxamide (CAS 681837-55-8)
- 2-(Pyrrolidin-1-yl)nicotinic acid hydrochloride (CAS 1052549-87-7)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com