5-Chloro-3-(3-fluorophenyl)-1,2-oxazole-4-carbaldehyde CAS 1188031-85-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1188031-85-7
Molecular FormulaC10H5ClFNO2
Molecular Weight225.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-3-(3-fluorophenyl)-1,2-oxazole-4-carbaldehyde CAS 1188031-85-7 chemical structure

Description

The occurrence of 5-Chloro-3-(3-fluorophenyl)-1,2-oxazole-4-carbaldehyde is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Chloro-3-(3-fluorophenyl)-1,2-oxazole-4-carbaldehyde (CAS 1188031-85-7), a certified reference material (molecular formula C10H5ClFNO2, MW 225.60 g/mol) for analytical method development and quality control.

5-Chloro-3-(3-fluorophenyl)-1,2-oxazole-4-carbaldehyde (C10H5ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H5ClFNO2
Molecular Weight225.60 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Cl-containing
Nitrogen Atoms1

Related Chloro Standards

Recommended Standards

Why CATO?