Epalrestat impurity 28 CAS 179027-75-9
| CAS No. | 179027-75-9 |
| Molecular Formula | C5H5NO3S2 |
| Molecular Weight | 191.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Epalrestat impurity 28 (C5H5NO3S2) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Epalrestat impurity 28 (CAS 179027-75-9), a pharmacopoeial impurity reference standard (molecular formula C5H5NO3S2, MW 191.23 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5NO3S2 |
| Molecular Weight | 191.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2008 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Epalrestat Standards
- Epalrestat Impurity 21 (CAS 5718-83-2)
- Epalrestat Impurity 12 (CAS 109801-00-5)
- Epalrestat impurity 33 (CAS 39486-57-2)
- Epalrestat Impurity 54 (CAS 1408072-62-7)
- Epalrestat impurity 32 (CAS CATO-C4X-223632)
- Epalrestat Impurity 19 (CAS 149789-77-5)
- Epalrestat Impurity 14 (CAS 31061-24-2)
- Epalrestat Impurity 61 (CAS CATO-C4X-223661)
Recommended Standards
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- (R)-N-Nitroso Anabasine (CAS 1795786-06-9)
- Relebactam Impurity 84 (CAS 1174069-42-1)
- Upadacitinib Impurity 9 (CAS CATO-C4X-24059)
- Difelikefalin Impurity 55 (CAS CATO-C4X-304155)
- Methyl 3-(5-methyl-3-phenylisoxazol-4-yl)-3-oxopropanoate (CAS 676348-61-1)
- (2-Chloro-4-(dimethylamino)-5-fluorophenyl)boronic acid (CAS 677742-00-6)
- Perindopril Impurity N3 (CAS 1004292-98-1)
- 5-(Difluoromethyl)indoline (CAS 1557656-96-8)
- 2-(4-Chlorophenyl)-2,3-dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid (CAS 285552-81-0)
- N,8-diphenyl-2,4-bis(trifluoromethyl)quinolin-7-amine (CAS 2472802-21-2)
- Delicious Peptide (bovine) (CAS 73984-05-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com