Letermovir Impurity 4 CAS 1791412-07-1
| CAS No. | 1791412-07-1 |
| Molecular Formula | C19H16F4N2O3 |
| Molecular Weight | 396.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Letermovir Impurity 4 (CAS 1791412-07-1) is a certified pharmaceutical impurity reference standard with the molecular formula C19H16F4N2O3 and a molecular weight of 396.34 g/mol.
Based on its molecular formula C19H16F4N2O3, Letermovir Impurity 4 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 396.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Letermovir Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16F4N2O3 |
| Molecular Weight | 396.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Letermovir Standards
- Letermovir Impurity 101 (CAS CATO-C4X-2915101)
- Letermovir impurity 108 (CAS CATO-C4X-2915108)
- Letermovir Impurity 16 (CAS CATO-C4X-291516)
- Letermovir Impurity 50 (CAS CATO-C4X-291550)
- Letermovir Impurity 69 (CAS CATO-C4X-291569)
- Letermovir impurity 111 (CAS CATO-C4X-2915111)
- Letermovir impurity 113 (CAS CATO-C4X-2915113)
- Letermovir Impurity 104 (CAS CATO-C4X-2915104)
Recommended Standards
- Methyl 4-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)-3-methylbenzoate (CAS 879288-18-3)
- N-[4-(2,4-Dichlorophenoxy)butyl]-4-(isopentyloxy)-aniline (CAS 1040688-99-0)
- Methyl 3-amino-6-(2H-1,3-benzodioxol-5-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate (CAS 625377-31-3)
- Methyl 16-iodohexadecanoate (CAS 106689-05-8)
- Allopurinol impurity 22 (CAS CATO-C4X-145822)
- Esomeprazole Impurity 68 (CAS 2512216-37-2)
- Ceftazidime Impurity 56 (CAS CATO-C4X-121256)
- β-Endorphin (6-31) (human) (CAS 77761-27-4)
- 1-(5-Amino-2-bromophenyl)ethanone (CAS 149914-98-7)
- 2,5-dichloro-4-methoxy-pyrimidine (CAS 5750-74-3)
- 3-(Morpholinomethyl)benzimidamide (CAS 1016782-70-9)
- 10,12-Pentacosadiynoic acid 66990-32-7 pentacosa-10,12-diynoic acid (CAS 66990-32-7)
- 3-Bromo-7-chloroimidazo[1,2-c]pyrimidine (CAS 1289047-59-1)
- Semaglutide impurity 57 (CAS 2773558-06-6)
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