Methyl 3-amino-6-(2H-1,3-benzodioxol-5-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate CAS 625377-31-3
| CAS No. | 625377-31-3 |
| Molecular Formula | C17H11F3N2O4S |
| Molecular Weight | 396.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 3-amino-6-(2H-1,3-benzodioxol-5-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate.
CATO supplies Methyl 3-amino-6-(2H-1,3-benzodioxol-5-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate (CAS 625377-31-3), a certified reference material (molecular formula C17H11F3N2O4S, MW 396.34 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Methyl 3-amino-6-(2H-1,3-benzodioxol-5-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 396.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H11F3N2O4S |
| Molecular Weight | 396.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- (3-Amino-6-(pyridin-3-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonyl)glycine (CAS 899370-08-2)
- Methyl 6-amino-5-cyano-2-(2-methoxy-2-oxoethyl)-4-(3-(trifluoromethyl)phenyl)-4H-pyran-3-carboxylate (CAS 865660-06-6)
- 2-Amino-3-(benzo[d]oxazol-2-yl)-6-methyl-4-nitro-1-pentyl-1,6-dihydro-7H-pyrrolo[2,3-d]pyridazin-7-one (CAS 748784-61-4)
- 6-Amino-2-(2,4-dimethylphenyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonic acid (CAS 93942-76-8)
- 2-(2-Amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine (CAS 1346527-98-7)
- 3-Amino-N-(3-methyl-4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CAS 1437315-24-6)
- 6-Amino-1-benzyl-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 554405-18-4)
- benzyl 2-((2-amino-3-carbamoylphenyl)carbamoyl)-2-methylpyrrolidine-1-carboxylate (CAS 912444-71-4)
Recommended Standards
- 5-(3-(Tert-butyl)-1-(2,4-dichlorobenzyl)-1H-pyrazol-5-yl)-4-methyl-4H-1,2,4-triazole-3-thiol (CAS 306937-18-8)
- Methyl 4-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)-3-methylbenzoate (CAS 879288-18-3)
- (E)-N'-(benzo[d][1,3]dioxol-5-ylmethylene)-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carbohydrazide (CAS 865659-79-6)
- Letermovir Impurity 4 (CAS 1791412-07-1)
- prop-2-ynyl N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]carbamate (CAS 2408797-69-1)
- (3-Bromophenyl)(2,5-dimethylphenyl)methanol (CAS 1282062-71-8)
- 3-Amino-3-(m-tolyl)propanamide (CAS 771527-85-6)
- 2-(4-(Methoxycarbonyl)phenyl)quinoline-4-carboxylic acid (CAS 1165799-99-4)
- 1-(1-Isobutyl-1H-pyrrol-3-yl)ethanone (CAS 133611-44-6)
- Ethyl 2-(3-Bromophenyl)-2,2-difluoroacetate (CAS 885068-75-7)
- 1-Bromo-5-methylhex-3-ene (CAS 99113-56-1)
- 1-Methyl-1h-pyrazole-3,4-diamine dihydrochloride (CAS 142109-60-2)
- N-(2H-1,3-Benzodioxol-5-yl)-7-chloroquinazolin-4-amine (CAS 477856-41-0)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
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