3-Bromo-2-fluoroquinoline CAS 179488-06-3
| CAS No. | 179488-06-3 |
| Molecular Formula | C9H5BrFN |
| Molecular Weight | 226.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Bromo-2-fluoroquinoline.
3-Bromo-2-fluoroquinoline (CAS 179488-06-3) is a high-purity analytical reference standard with the molecular formula C9H5BrFN and a molecular weight of 226.05 g/mol.
The molecular framework of 3-Bromo-2-fluoroquinoline (C9H5BrFN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5BrFN |
| Molecular Weight | 226.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-7-fluoroquinoline (CAS 1070879-29-6)
- 5-Bromo-6-fluoroquinoline (CAS 107224-21-5)
- 1-Bromo-3-fluoroisoquinoline (CAS 1076-36-4)
- 5-Bromo-8-fluoroquinoline (CAS 1133115-78-2)
- 1-Bromo-6-fluoroisoquinoline (CAS 1196151-59-3)
- 1-Bromo-7-fluoroisoquinoline (CAS 1207448-24-5)
- 1-Bromo-5-fluoroisoquinoline (CAS 1207448-30-3)
- 5-Bromo-7-fluoroquinoline (CAS 1239462-97-5)
Recommended Standards
- 6-Bromo-4-fluoroquinoline (CAS 1713240-89-1)
- 7-Bromo-1-fluoroisoquinoline (CAS 1801986-20-8)
- (3-(Tert-butoxymethyl)-4-fluorophenyl)boronic acid (CAS 1704067-02-6)
- 2-Chloro-5-(chloromethyl)-4-(difluoromethyl)-3-methylpyridine (CAS 1804377-29-4)
- 1-(5-Ethoxy-2-hydroxyphenyl)ethan-1-one (CAS 56414-14-3)
- tert-butyl 7-chloro-3,4-dihydro-2H-1,8-naphthyridine-1-carboxylate (CAS 679392-23-5)
- N-(5-Hydroxy-3-phenylpentyl)cyclopropanecarboxamide (CAS 1798457-16-5)
- Methyl 3-(propylcarbamoyl)benzoate (CAS 925617-80-7)
- 2-(4-Bromophenyl)propan-2-amine hydrochloride (CAS 1173047-86-3)
- 2-(3-(Furan-2-yl)-6-oxopyridazin-1(6H)-yl)-N-(4-morpholinophenyl)propanamide (CAS 1286695-23-5)
- 1-(2-Chloro-6-fluorophenyl)cyclohexane-1-carboxylic acid (CAS 214263-04-4)
- 2,3-Dichloro-4-iodopyridine (CAS 889865-45-6)
- 4-(2-Bromoacetyl)-3-hydroxyfuran-2(5H)-one (CAS 99983-31-0)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
Why CATO?
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