4-(1,1,1-Trifluoro-2-hydroxypropan-2-yl)phenol CAS 179632-68-9
| CAS No. | 179632-68-9 |
| Molecular Formula | C9H9F3O2 |
| Molecular Weight | 206.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(1,1,1-Trifluoro-2-hydroxypropan-2-yl)phenol (CAS 179632-68-9) is a high-purity analytical reference standard with the molecular formula C9H9F3O2 and a molecular weight of 206.16 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-(1,1,1-Trifluoro-2-hydroxypropan-2-yl)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 206.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(1,1,1-Trifluoro-2-hydroxypropan-2-yl)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H9F3O2 |
| Molecular Weight | 206.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F-containing |
Related Trifluoro Standards
- 2-(1,1,1-Trifluoro-2-methylpropan-2-yl)-4H-pyran-4-one (CAS 1357476-64-2)
- (R)-2,2,2-Trifluoro-1-(4-methoxyphenyl)ethan-1-ol (CAS 80446-58-8)
- (S)-2,2,2-Trifluoro-1-(4-methoxyphenyl)ethan-1-ol (CAS 80446-59-9)
- 2,2,2-Trifluoro-1-(2-methoxypyridin-3-yl)ethanamine (CAS 1060807-17-1)
- 2,2,2-trifluoro-1-(6-methoxypyridin-2-yl)ethan-1-amine (CAS 1060807-19-3)
- 2,2,2-Trifluoro-1-(6-methoxypyridin-3-yl)ethan-1-amine (CAS 1060807-22-8)
- 2,2,2-trifluoro-1-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethan-1-one (CAS 1306606-56-3)
- 2,2,2-trifluoro-1-[1-(propan-2-yl)-1H-pyrazol-4-yl]ethan-1-one (CAS 1342725-36-3)
Recommended Standards
- 1-[4-(Trifluoromethyl)phenyl]ethane-1,2-diol (CAS 175605-64-8)
- 3,5-Dimethyl-4-(trifluoromethoxy)phenol (CAS 1803791-38-9)
- 1-Methoxymethoxy-4-(trifluoromethyl)benzene (CAS 174265-24-8)
- 6-Nitro-1H-benzo[d]imidazole-4-carboxamide (CAS 1805873-85-1)
- 3-Amino-4-(trifluoromethyl)phenylboronic acid (CAS 2377607-83-3)
- 5'-deoxy-5-fluoro-N-(methoxycarbonyl)-Cytidine (CAS 296248-49-2)
- 6-Iodoquinolin-7-yl dimethylcarbamate (CAS 829666-48-0)
- 2-(4-Chlorophenyl)-5-methyl-1H-benzoimidazole (CAS 53314-17-3)
- 3-(2-Bromo-5-ethoxy-4-methoxyphenyl)acrylic acid (CAS 423747-21-1)
- Entacapone impurity 51 (CAS CATO-C4X-162951)
- 2-Nitrothiazole-5-carboxylic acid (CAS 59521-24-3)
- 6-(5-chlorothiophen-2-yl)pyridin-3-amine (CAS 438585-65-0)
- 5-(sec-Butyl)-2,5-dihydro-1H-pyrrole-2,4-diol (CAS 903517-07-7)
- Hexapeptide-11 (CAS 100684-36-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com