3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea CAS 1796882-68-2
| CAS No. | 1796882-68-2 |
| Molecular Formula | C24H18ClF3N4O2 |
| Molecular Weight | 486.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796882-68-2), a certified reference material (molecular formula C24H18ClF3N4O2, MW 486.87 g/mol) for analytical method development and quality control.
Based on its molecular formula C24H18ClF3N4O2, 3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 486.87 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H18ClF3N4O2 |
| Molecular Weight | 486.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 1-[2-Chloro-4-(trifluoromethyl)phenyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796904-73-8)
- 1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]urea (CAS 1796920-11-0)
- 2-((4-Chloro-N-(3-(trifluoromethyl)phenyl)phenyl)sulfonamido)-N-(2-fluorophenyl)acetamide (CAS 337922-23-3)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(1E)-{[(4-nitrophenyl)methoxy]amino}methylidene]piperazine-1-carboxamide (CAS 339029-32-2)
- Ethyl 10-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-9,11-dioxo-3-oxa-4,10-diazatetracyclo[5.5.1.0^{2,6}.0^{8,12}]tridec-4-ene-5-carboxylate (CAS 321385-52-8)
- 2-Chloro-N1,N4-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)terephthalamide (CAS 70-09-7)
- 1-Chloro-4-(4-chloro-1,1,2,2,3,3,4,4-octafluorobutoxy)-1,1,2,2,3,3,4,4-octafluorobutane (CAS 149697-40-5)
- 1-(2-{[4-(3-chloro-4-methoxyphenyl)-5-phenyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetyl)piperidine-4-carboxylic acid (CAS 731801-15-3)
Recommended Standards
- Norepinephrine impurity 145 (CAS CATO-C4X-1514145)
- 4-Acetamidophenyl 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzene-1-sulfonate (CAS 338400-17-2)
- 3-Acetamidophenyl 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzene-1-sulfonate (CAS 338414-10-1)
- (R)-Methyl 3-chloro-3'-fluoro-4'-(1-(1-(2,2,2-trifluoroacetamido)cyclopropanecarboxamido)ethyl)-[1,1'-biphenyl]-2-carboxylate (CAS 578727-68-1)
- 2-Amino-4-(4-(tert-butyl)phenyl)-5-methylthiophene-3-carboxamide (CAS 861451-49-2)
- N-(2-Chlorophenyl)-6-(piperidin-4-yl)imidazo[1,2-a]pyridine-3-carboxamide oxalate (CAS 1198408-78-4)
- 6-Acetyl-4,4-dimethylthiochroman (CAS 88579-23-1)
- 4-(3-(Methoxymethyl)piperidin-1-yl)aniline (CAS 1698150-96-7)
- ethyl 5,5-dimethyl-4-oxooxolane-3-carboxylate (CAS 1803608-60-7)
- Milrinone Impurity 2 (CAS 400063-10-7)
- 4,6-Dimethyl-2-((3-(trifluoromethyl)benzyl)oxy)nicotinonitrile (CAS 866137-07-7)
- tert-Butyl 1-(aminomethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate (CAS 1250997-62-6)
- (S)-3-Amino-3-(2-bromo-4-(trifluoromethyl)phenyl)propan-1-ol (CAS 1388085-94-6)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
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