Cyclophosphamide EP Impurity A CAS 1797009-12-1

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.1797009-12-1
Molecular FormulaC7H16ClN2O3P
Molecular Weight242.64 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cyclophosphamide EP Impurity A CAS 1797009-12-1 chemical structure

Description

Cyclophosphamide EP Impurity A (CAS 1797009-12-1) is a certified pharmaceutical impurity reference standard with the molecular formula C7H16ClN2O3P and a molecular weight of 242.64 g/mol.

Structurally, Cyclophosphamide EP Impurity A (C7H16ClN2O3P) contains an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 0.5, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 242.64 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H16ClN2O3P
Molecular Weight242.64 g/mol
Purity>90%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)0.5
CAS Registry Year (est.)1994
Halogen ContentCl-containing
Nitrogen Atoms2

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