Cyclophosphamide Impurity 25 CAS 2387771-94-8
| CAS No. | 2387771-94-8 |
| Molecular Formula | C9H21N2O4P |
| Molecular Weight | 252.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Cyclophosphamide Impurity 25 (CAS 2387771-94-8) is a certified pharmaceutical impurity reference standard with the molecular formula C9H21N2O4P and a molecular weight of 252.25 g/mol.
The molecular framework of Cyclophosphamide Impurity 25 (C9H21N2O4P) is characterized by an amide group, a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cyclophosphamide Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H21N2O4P |
| Molecular Weight | 252.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 0.5 |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 2 |
Related Cyclophosphamide Standards
- Cyclophosphamide impurity 35 (CAS CATO-C4X-230635)
- Cyclophosphamide Impurity 13 (CAS 127-88-8)
- Cyclophosphamide Impurity 4 (CAS 2810251-24-0)
- Cyclophosphamide (CAS 50-18-0)
- Cyclophosphamide EP Impurity A (CAS 1797009-12-1)
- Cyclophosphamide EP Impurity D (CAS 158401-52-6)
- Cyclophosphamide-d8 (CAS 1178903-96-2)
- Cyclophosphamide Impurity 21 (CAS 2517939-95-4)
Recommended Standards
- Riociguat Impurity 8 (CAS 256376-65-5)
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- Vericiguat Impurity 89 (CAS CATO-C4X-289689)
- N-(3-Methylisothiazol-5-yl)-4-nitro-1H-pyrrole-2-carboxamide (CAS 478493-09-3)
- Tetrabenazine Impurity 48 (CAS 1214267-46-5)
- Pimobendan Impurity 2 (CAS 2138391-23-6)
- Enzalutamide Impurity 44 (CAS 24115-24-0)
- 5,7-Dimethoxy-2-methyl-chromen-4-one (CAS 26213-83-2)
- 3-(Ethylsulfonyl)-4-(3-fluorophenyl)-1H-pyrazole (CAS 1713477-37-2)
- 2-((4-Chlorophenyl)(hydroxy)methylene)malononitrile (CAS 5593-28-2)
- 2-(Difluoromethyl)-4-fluoro-3-methoxypyridine-5-carboxaldehyde (CAS 1806925-23-4)
- 3-(Bromomethyl)-2-fluoropyridine hydrobromide (CAS 31140-59-7)
- (Z)-(4-Hydroxy-2-buten-2-yl)boronic Acid Pinacol Ester (CAS 1008752-03-1)
- Lixisenatide (CAS 320367-13-3（free base）)
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