Sitafloxacin impurity 11 CAS 1799439-05-6
| CAS No. | 1799439-05-6 |
| Molecular Formula | C7H8O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Sitafloxacin impurity 11 (CAS 1799439-05-6, C7H8O3SC3H6FN) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Sitafloxacin impurity 11 (C7H8O3SC3H6FN) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C7H8O3S C3H6FN |
| Molecular Weight | 247.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Sitafloxacin Standards
- Sitafloxacin Impurity 22 (CAS 101987-86-4)
- Sitafloxacin Impurity 25 (CAS 105919-35-5)
- Sitafloxacin impurity 90 (CAS 112062-51-8)
- Sitafloxacin Impurity 27 (CAS 119385-80-7)
- Sitafloxacin Impurity 17 (CAS 127199-00-2)
- Sitafloxacin Isomer Impurity 4(RSR) (CAS 127199-06-8)
- Sitafloxacin impurity 85 (CAS 127199-06-8（free base）)
- Sitafloxacin Impurity 23 (CAS 127199-15-9)
Recommended Standards
- Silodosin Impurity 31 (CAS CATO-C4X-175431)
- Benzbromarone EP Impurity C (CAS 1477-19-6)
- Cabozantinib Impurity 8 (CAS 213699-53-7)
- Momordin?Ic (CAS 96990-18-0)
- (2S,4R)-1-(tert-Butoxycarbonyl)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-2-carboxylic acid (CAS 149814-40-4)
- 4-{[2-(pyrrolidin-1-yl)pyridin-3-yl]carbamoyl}butanoic acid (CAS 1183368-87-7)
- 2-(Cyclohex-1-en-1-yl)-N-(4-methoxybenzyl)ethan-1-amine hydrochloride (CAS 1048640-95-4)
- (2R,3S)-2-(Hydroxymethyl)tetrahydrofuran-3-ol (CAS 91547-59-0)
- cis-4-Heptenal (CAS 6728-31-0)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
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