[3a<I>R</I>-[2(3′a<I>R</I>*,8′a<I>S</I>*),3′aβ,8′aβ]] -(+)-2,2′-methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-]oxazole] CAS 180186-94-1

Purity 97%+In StockPharmaceutical Standards
CAS No.180186-94-1
Molecular FormulaC21H30N2O2
Molecular Weight342.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

[3a<I>R</I>-[2(3′a<I>R</I>*,8′a<I>S</I>*),3′aβ,8′aβ]] -(+)-2,2′-methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-]oxazole] CAS 180186-94-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 342.48 g/mol gives [3a<I>R</I>-[2(3′a<I>R</I>*,8′a<I>S</I>*),3′aβ,8′aβ]] -(+)-2,2′-methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-]oxazole] distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies [3a<I>R</I>-[2(3′a<I>R</I>*,8′a<I>S</I>*),3′aβ,8′aβ]] -(+)-2,2′-methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-]oxazole] (CAS 180186-94-1), a certified reference material (molecular formula C21H30N2O2, MW 342.48 g/mol) for analytical method development and quality control.

The molecular framework of [3a<I>R</I>-[2(3′a<I>R</I>*,8′a<I>S</I>*),3′aβ,8′aβ]] -(+)-2,2′-methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-]oxazole] (C21H30N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), [3a<I>R</I>-[2(3′a<I>R</I>*,8′a<I>S</I>*),3′aβ,8′aβ]] -(+)-2,2′-methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-]oxazole] meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC21H30N2O2
Molecular Weight342.48 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2008
Nitrogen Atoms2

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