(3a<I>S</I>,3′a<I>S</I>,8a<I>R,</I>8′a<I>R</I>)-2,2′ -Methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-<I>d</I>]oxazole] CAS 175166-49-1

Purity 97%+In StockPharmaceutical Standards
CAS No.175166-49-1
Molecular FormulaC21H30N2O2
Molecular Weight342.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3a<I>S</I>,3′a<I>S</I>,8a<I>R,</I>8′a<I>R</I>)-2,2′ -Methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-<I>d</I>]oxazole] CAS 175166-49-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3a<I>S</I>,3′a<I>S</I>,8a<I>R,</I>8′a<I>R</I>)-2,2′ -Methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-<I>d</I>]oxazole].

(3a<I>S</I>,3′a<I>S</I>,8a<I>R,</I>8′a<I>R</I>)-2,2′ -Methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-<I>d</I>]oxazole] (CAS 175166-49-1) is a high-purity analytical reference standard with the molecular formula C21H30N2O2 and a molecular weight of 342.48 g/mol.

The molecular framework of (3a<I>S</I>,3′a<I>S</I>,8a<I>R,</I>8′a<I>R</I>)-2,2′ -Methylenebis[3a,8a-dihydro-8<I>H</I>-indeno[1,2-<I>d</I>]oxazole] (C21H30N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H30N2O2
Molecular Weight342.48 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2007
Nitrogen Atoms2

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