Phenyltris(dimethylsiloxy)silane CAS 18027-45-7

Purity 97%+In StockPharmaceutical Standards
CAS No.18027-45-7
Molecular FormulaC12H26O3Si4
Molecular Weight330.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Phenyltris(dimethylsiloxy)silane CAS 18027-45-7 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Phenyltris(dimethylsiloxy)silane (CAS 18027-45-7) is a high-purity analytical reference standard with the molecular formula C12H26O3Si4 and a molecular weight of 330.68 g/mol.

The molecular framework of Phenyltris(dimethylsiloxy)silane (C12H26O3Si4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO manufactures Phenyltris(dimethylsiloxy)silane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H26O3Si4
Molecular Weight330.68 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1962

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