2-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamide CAS 1022964-40-4
| CAS No. | 1022964-40-4 |
| Molecular Formula | C13H10ClF3N4O |
| Molecular Weight | 330.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamide (CAS 1022964-40-4), molecular formula C13H10ClF3N4O and molecular weight 330.69 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamide (C13H10ClF3N4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 330.69 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10ClF3N4O |
| Molecular Weight | 330.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 2-Chloro-N-(3-(trifluoromethoxy)benzyl)nicotinamide (CAS 1023518-67-3)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methylnicotinohydrazide (CAS 1024115-40-9)
- 4-((4-Chloro-5-(trifluoromethyl)pyrimidin-2-yl)amino)-N-methylbenzamide (CAS 1073160-19-6)
- (E)-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methylidene](methoxy)amine (CAS 1092343-94-6)
- 8-Chloro-2-(2,2,2-trifluoroacetyl)-1,3,4,5-tetrahydrobenzo[b][1,6]naphthyridin-10(2H)-one (CAS 1325306-24-8)
- 4-((4-Chloro-3-(trifluoromethyl)phenoxy)methyl)benzoic acid (CAS 1355637-18-1)
- Methyl 2-[4-chloro-3-(trifluoromethyl)phenoxy]benzoate (CAS 136562-55-5)
- Methyl 2-chloro-4-[4-(trifluoromethoxy)phenyl]benzoate (CAS 1820675-34-0)
Recommended Standards
- Phenyltris(dimethylsiloxy)silane (CAS 18027-45-7)
- 1-{[5-chloro-2-(difluoromethoxy)phenyl]methyl}-5-nitro-1,2-dihydropyridin-2-one (CAS 1241307-74-3)
- 6-Chloro-9-(2-fluorobenzyl)-2-(trifluoromethyl)-9H-purine (CAS 122488-70-4)
- N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-cyano-5-methylisoxazole-4-carboxamide (CAS 400076-14-4)
- 1H-Imidazo[4,5-g]quinazoline (CAS 53974-23-5)
- 2,7-Diamino-4-(pyridin-3-yl)-4H-chromene-3-carbonitrile (CAS 314767-75-4)
- 1-(Cyclopropylmethyl)-2-oxo-2,3-dihydro-1h-1,3-benzodiazole-5-carboxylic acid (CAS 1019342-55-2)
- N-Nitroso Relebactam Impurity 51 (CAS CATO-C4X-214451)
- Atrasentan Impurity 155 (CAS 1073831-62-5)
- 3-Isobutylmorpholine (CAS 959238-46-1)
- N,N-Diethyldodecanamide (CAS 3352-87-2)
- 2-[(4-aminophenyl)methoxy]ethan-1-ol (CAS 1019516-04-1)
- 4-(3-Methylbenzo[b]thien-2-yl)-2-thiazolamine (CAS 21036-85-1)
- (Des-Thr7)-Glucagon trifluoroacetate salt (CAS 1802078-28-9)
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