Vildagliptin Impurity 29 CAS 1803168-08-2

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1803168-08-2
Molecular FormulaC7H10Cl2N2O2
Molecular Weight225.07 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Vildagliptin Impurity 29 CAS 1803168-08-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 225.07 g/mol gives Vildagliptin Impurity 29 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Vildagliptin Impurity 29 (CAS 1803168-08-2), a pharmacopoeial impurity reference standard (molecular formula C7H10Cl2N2O2, MW 225.07 g/mol) used for the identification and quantification of trace impurities in APIs.

Vildagliptin Impurity 29 (C7H10Cl2N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Vildagliptin Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H10Cl2N2O2
Molecular Weight225.07 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1995
Halogen ContentCl-containing
Nitrogen Atoms2

Related Vildagliptin Standards

Recommended Standards

Why CATO?