Esomeprazole H215 Impurity Sodium Salt CAS 1803449-15-1
| CAS No. | 1803449-15-1 |
| Molecular Formula | C16H15N3O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Esomeprazole H215 Impurity Sodium Salt (CAS 1803449-15-1), a pharmacopoeial impurity reference standard (molecular formula C16H15N3O3SNa, MW 352.36 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Esomeprazole H215 Impurity Sodium Salt (C16H15N3O3SNa) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15N3O3S 2*Na |
| Molecular Weight | 352.36 g/mol |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Esomeprazole Standards
- Esomeprazole Impurity 70 (CAS 103876-98-8)
- Esomeprazole Impurity 71 (CAS 1076199-93-3)
- Esomeprazole Impurity 79 (CAS 1080689-87-7)
- Esomeprazole Impurity 116 (CAS 109371-19-9)
- Esomeprazole Impurity 106 (CAS 110464-72-7)
- Esomeprazole Impurity 31 (CAS 1114596-75-6)
- EsoMeprazole (CAS 119141-88-7)
- Esomeprazole EP Impurity F (CAS 119141-89-8)
Recommended Standards
- Relugolix Impurity 204 (CAS CATO-C4X-2429204)
- Temozolomide Impurity 15 (CAS 100607-08-7)
- Lornoxicam impurity 60 (CAS 123252-96-0)
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- 2-Hydroxy-5-nitrobenzaldehyde compound with dipentylamine (1:1) (CAS 172265-68-8)
- 3,5-dimethyl-4-[2-oxo-2-(piperidin-1-yl)ethoxy]benzoic acid (CAS 1039310-65-0)
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- 4-(2,4-Di-tert-pentylphenoxy)butanenitrile (CAS 36268-65-2)
- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com