2-Amino-3-methyl-6-(trifluoromethoxy)isonicotinonitrile CAS 1803549-29-2
| CAS No. | 1803549-29-2 |
| Molecular Formula | C8H6F3N3O |
| Molecular Weight | 217.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 217.15 g/mol gives 2-Amino-3-methyl-6-(trifluoromethoxy)isonicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-3-methyl-6-(trifluoromethoxy)isonicotinonitrile (CAS 1803549-29-2), molecular formula C8H6F3N3O and molecular weight 217.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Amino-3-methyl-6-(trifluoromethoxy)isonicotinonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 217.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6F3N3O |
| Molecular Weight | 217.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-5-(trifluoromethoxy)benzimidazole (CAS 132877-27-1)
- (2S)-2-amino-3-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid (S)-(-)-5-fluorowillardiine (S)-F-Willardiine (S)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid 140187-23-1 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID 3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine 3-(5-fluorouracil-1-yl)-L-alanine 5-Fluorowillardiine CHEBI:42549 (CAS 140187-23-1)
- 1-Amino-6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile (CAS 72567-46-5)
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Recommended Standards
- 9-Methyl-6-(trifluoromethyl)-9h-purin-2-amine (CAS 1744-14-5)
- 2-(3-Methyl-6-oxo-5-(trifluoromethyl)pyridazin-1(6H)-yl)acetonitrile (CAS 1823330-10-4)
- 1-(Bromomethyl)-3-(tert-butyl)bicyclo[1.1.1]Pentane (CAS 162374-92-7)
- (Z)-1-Bromo-3,7-dimethylocta-2,6-diene (CAS 25996-10-5)
- N-(2,4-difluorophenyl)-4-(4-phenylthiazol-2-yl)benzamide (CAS 321429-82-7)
- 3-tert-Butyl-2-hydroxy-5-methoxybenzaldehyde (CAS 123013-13-8)
- N-(5-Amino-2-methylphenyl)-3,5-dichlorobenzamide (CAS 926210-73-3)
- Tert-butyl 5-amino-1h-1,2,4-triazole-3-carboxylate (CAS 1339749-97-1)
- Glycyrrhizic Acid (CAS 1405-86-3)
- Ethyl N-(tert-butoxycarbonyl)-3-iodophenylalaninate (CAS 1922842-97-4)
- Pf-4989216 (CAS 1276553-09-3)
- Ethyl 1-benzyl-3-methyl-1H-pyrazole-4-carboxylate (CAS 1344045-94-8)
- (2R,3R)-7-bromo-6-(4-fluorophenyl)-2,3-dimethyl-2,3-dihydropyrazolo[5,1-b]oxazole (CAS 1429893-64-0)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
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