N-(2-Cyano-3-fluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide CAS 1803600-27-2
| CAS No. | 1803600-27-2 |
| Molecular Formula | C17H8F4N4O2 |
| Molecular Weight | 376.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(2-Cyano-3-fluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide (CAS 1803600-27-2) is a high-purity analytical reference standard with the molecular formula C17H8F4N4O2 and a molecular weight of 376.26 g/mol.
N-(2-Cyano-3-fluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide (C17H8F4N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(2-Cyano-3-fluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H8F4N4O2 |
| Molecular Weight | 376.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
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Recommended Standards
- tert-Butyl (2-(4-bromo-2-fluorophenoxy)ethyl)(isopropyl)carbamate (CAS 1704097-32-4)
- ((2R,3S,4R,5R)-5-(6-Amino-8-(methylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 61370-73-8)
- 4,4'-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4-diyl)dimorpholine (CAS 1370351-45-3)
- (2E)-N-(4-Bromo-2-fluorophenyl)-3-[4-(2-methylpropyl)phenyl]prop-2-enamide (CAS 329778-56-5)
- 5-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-(4-methoxyphenyl)-2-methyl-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 317833-31-1)
- 5-bromo-2-(chloromethyl)pyrimidine (CAS 944903-00-8)
- (3S,8AS)-3-methyl-1-thioxohexahydropyrrolo[1,2-a]pyrazin-4(1H)-one (CAS 167391-76-6)
- 3-Amino-N-(4-fluorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496801-80-0)
- {[3-(Benzyloxy)phenyl]methyl}(propan-2-yl)amine (CAS 760910-17-6)
- 4-(4-(4-Hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl)benzene-1,2-diol (CAS 40951-69-7)
- Baclofen EP Impurity B (CAS 1141-23-7)
- 4-Amino-N-methyl-N-(2-(pyridin-4-yl)ethyl)butanamide hydrochloride (CAS 1828296-94-1)
- 6-chloro-[1,3]thiazolo[4,5-b]pyrazin-2-amine (CAS 1440427-74-6)
- Insulin degludec (CAS 844439-96-9)
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