Baclofen EP Impurity B CAS 1141-23-7
| CAS No. | 1141-23-7 |
| Molecular Formula | C11H12ClNO3 |
| Molecular Weight | 241.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Baclofen EP Impurity B (CAS 1141-23-7), a pharmacopoeial impurity reference standard (molecular formula C11H12ClNO3, MW 241.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Baclofen EP Impurity B is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 241.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Baclofen EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO3 |
| Molecular Weight | 241.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Baclofen Standards
- Baclofen Impurity 37 (CAS CATO-C4X-101237)
- Baclofen Impurity 38 (CAS CATO-C4X-101238)
- Baclofen Impurity 41 (CAS 159156-84-0)
- Baclofen impurity 12 (CAS 232597-00-1)
- Baclofen impurity 18 (CAS CATO-C4X-101218)
- Baclofen Impurity 40 (CAS CATO-C4X-101240)
- Baclofen EP Impurity C (CAS 35271-74-0)
- Baclofen impurity 7 (CAS 103857-58-5)
Recommended Standards
- N-acetyl-2-chloro- L-Phenylalanine (CAS 103522-34-5)
- 2-Chloro-N-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-acetamide 757220-20-5 9281AE C11H12ClNO3 (CAS 757220-20-5)
- 72544-42-4 Methyl 2-[(2-chloropropanoyl)amino]benzoate MFCD12142206 (CAS 72544-42-4)
- 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoyl chloride 3-Maleimidobenzoic acid chloride 61960-57-4 (CAS 61960-57-4)
- Rebamipide Impurity 10 (CAS CATO-C4X-152310)
- Domperidone Impurity 32 (CAS CATO-C4X-142032)
- Lumateperone Impurity 32 (CAS CATO-C4X-220132)
- 2-Amino-6-(2-fluorophenyl)nicotinic acid (CAS 1708268-92-1)
- 2-(2-(Trifluoromethyl)pyridin-4-yl)acetonitrile (CAS 1227591-90-3)
- 1-(2-(2-Hydroxyethoxy)ethyl)-3-phenyl-2-thioxoimidazolidin-4-one (CAS 55036-71-0)
- 2-Methyl-4,5-dihydrooxazole-4-carboxylic acid (CAS 114482-46-1)
- 3-Allyl-1,3,5-triazinane-2,4-dione (CAS 104732-57-2)
- Resmetirom Impurity 38 (CAS CATO-C4X-291238)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com