2,2-difluoro-2-(1,3-thiazol-2-yl)ethan-1-ol CAS 1803604-35-4
| CAS No. | 1803604-35-4 |
| Molecular Formula | C5H5F2NOS |
| Molecular Weight | 165.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2,2-difluoro-2-(1,3-thiazol-2-yl)ethan-1-ol (CAS 1803604-35-4), a certified reference material (molecular formula C5H5F2NOS, MW 165.16 g/mol) for analytical method development and quality control.
The molecular framework of 2,2-difluoro-2-(1,3-thiazol-2-yl)ethan-1-ol (C5H5F2NOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2,2-difluoro-2-(1,3-thiazol-2-yl)ethan-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5F2NOS |
| Molecular Weight | 165.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related difluoro Standards
- 2,2-Difluoro-1-(1,3-thiazol-2-yl)ethan-1-ol (CAS 1312535-16-2)
- 2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)ethan-1-amine (CAS 1048963-32-1)
- 2,2-Difluoro-N-((tetrahydrofuran-2-yl)methyl)ethan-1-amine (CAS 1182935-72-3)
- 2,2-Difluoro-N-methoxy-N-methylcyclopropane-1-carboxamide (CAS 1202774-49-9)
- 3,3-Difluoro-4-(hydroxymethyl)piperidin-2-one (CAS 1258639-19-8)
- 3,3-Difluoro-4-piperidinecarboxylic acid (CAS 1303974-04-0)
- (S)-4,4-difluoro-1-methylpyrrolidine-2-carboxylic acid (CAS 1305325-21-6)
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Recommended Standards
- (5-(Difluoromethyl)thiazol-2-yl)methanol (CAS 1784808-26-9)
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- (1R,6R,7R)-7-(trifluoromethyl)-2-azabicyclo[4.1.0]Heptane (CAS 1821707-36-1)
- 4-(3,5-Dimethylphenyl)but-3-yn-2-one (CAS 2628359-89-5)
- tert-Butyl (9-hydroxynonyl)carbamate (CAS 1397043-36-5)
- [(1S)-1-phenylethyl](propan-2-yl)amine hydrochloride (CAS 116297-12-2)
- AB-001 (CAS 1345973-49-0)
- 3-Propyl-1,3,8-triazaspiro[4.5]Decane-2,4-dione (CAS 1226053-97-9)
- 5-(3-Chlorophenyl)-2-(trifluoromethyl)furan-3-carboxylic acid (CAS 242812-02-8)
- 1-[(4-methylphenyl)sulfonyl]-2,3-dihydroquinolin-4(1h)-one (CAS 14278-37-6)
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