2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)ethan-1-amine CAS 1048963-32-1
| CAS No. | 1048963-32-1 |
| Molecular Formula | C7H13F2NO |
| Molecular Weight | 165.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)ethan-1-amine (CAS 1048963-32-1), molecular formula C7H13F2NO and molecular weight 165.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2,2-Difluoro-2-(tetrahydro-2H-pyran-4-yl)ethan-1-amine is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 165.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H13F2NO |
| Molecular Weight | 165.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,2-Difluoro-N-((tetrahydrofuran-2-yl)methyl)ethan-1-amine (CAS 1182935-72-3)
- (4,4-Difluoro-1,2-dimethylpyrrolidin-2-yl)methanol (CAS 2417920-29-5)
- (4,4-Difluoro-5-methylpiperidin-3-yl)methanol (CAS 2366182-30-9)
- (5,5-Difluoro-1-methylpiperidin-3-yl)methanol (CAS 2757097-14-4)
- (5,5-Difluoro-2-methylpiperidin-3-yl)methanol (CAS 2366182-53-6)
- 2,2-difluoro-2-(pyridin-2-yl)ethan-1-ol (CAS 267875-65-0)
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Recommended Standards
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- 3,4,5-Trimethoxybenzyl Chloride (CAS 3840-30-0)
- 71125-54-7 N,N-Dipropyl-1,3,4-thiadiazole-2,5-diamine MFCD15732312 (CAS 71125-54-7)
- 2-Amino-5-formylbenzonitrile (CAS 22782-40-7)
- 2-Thioxo-1,2-dihydropyridine-3-carboxamide (CAS 50596-67-3)
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