5-(4-chloro-3-fluorophenyl)-1,2,4-triazin-3-amine CAS 1803605-27-7
| CAS No. | 1803605-27-7 |
| Molecular Formula | C9H6ClFN4 |
| Molecular Weight | 224.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(4-chloro-3-fluorophenyl)-1,2,4-triazin-3-amine (CAS 1803605-27-7) is a high-purity analytical reference standard with the molecular formula C9H6ClFN4 and a molecular weight of 224.62 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 5-(4-chloro-3-fluorophenyl)-1,2,4-triazin-3-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 224.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6ClFN4 |
| Molecular Weight | 224.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
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Recommended Standards
- 3-Chloro-1-(2-fluorophenyl)pyrazin-2(1H)-one (CAS 1707399-39-0)
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- sodium 2-(5-bromopyrimidin-4-yl)acetate (CAS 1803611-95-1)
- 4-Hydrazino-1-methylpyrazole Dihydrochloride (CAS 1803599-63-4)
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