2-(Bromomethyl)-6-(difluoromethyl)pyridine-4-carboxylic acid CAS 1803692-75-2
| CAS No. | 1803692-75-2 |
| Molecular Formula | C8H6BrF2NO2 |
| Molecular Weight | 266.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 266.04 g/mol gives 2-(Bromomethyl)-6-(difluoromethyl)pyridine-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(Bromomethyl)-6-(difluoromethyl)pyridine-4-carboxylic acid (CAS 1803692-75-2), a certified reference material (molecular formula C8H6BrF2NO2, MW 266.04 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 2-(Bromomethyl)-6-(difluoromethyl)pyridine-4-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 266.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Bromomethyl)-6-(difluoromethyl)pyridine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrF2NO2 |
| Molecular Weight | 266.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 4-(Bromomethyl)-3-(difluoromethyl)-6-hydroxypicolinaldehyde (CAS 1805088-69-0)
- 2-(Bromomethyl)-4-(difluoromethyl)-5-hydroxypyridine-3-carboxaldehyde (CAS 1805091-89-7)
- 1-Bromomethyl-4-nitro-naphthalene (CAS 16855-41-7)
- 55715-03-2 4-Bromomethyl-3-nitrobenzoic acid Benzoic acid, 4-(bromomethyl)-3-nitro- BNBA (CAS 55715-03-2)
- 2-(Bromomethyl)-6-(3-fluorophenyl)pyridine (CAS 1227511-54-7)
- 2-[4-(Bromomethyl)phenyl]-5-fluoropyridine (CAS 1257426-56-4)
- 4-(Bromomethyl)-5-methyl-3-p-tolylisoxazole (CAS 1159981-12-0)
- 6-(Bromomethyl)-1-ethylquinolin-2(1H)-one (CAS 133032-63-0)
Recommended Standards
- ethyl 4-iodo-1H-pyrazole-3-carboxylate (CAS 179692-08-1)
- 6-Bromo-5-(difluoromethyl)-2-methoxynicotinaldehyde (CAS 1804460-91-0)
- Methyl 2-amino-4-bromo-3,6-difluorobenzoate (CAS 1692564-79-6)
- 2-Bromo-6-(difluoromethyl)-5-methoxynicotinaldehyde (CAS 1804460-98-7)
- 4-Isobutoxyaniline (CAS 5198-04-9)
- 1-(2-Bromoallyl)-3-methylpiperidine (CAS 1306746-95-1)
- 3,4,5-Tris(octyloxy)benzoic acid (CAS 157980-09-1)
- (S)-1-Boc-2-(Hydroxymethyl)piperazine (CAS 1030377-21-9)
- Ethyl 6-oxooctahydro-3aH-indene-3a-carboxylate (CAS 97180-66-0)
- 4-(2-Aminoethyl)-1,3-thiazol-2-amine dihydrobromide (CAS 142437-66-9)
- 4-Bromo-2-methyl-6-(trifluoromethoxy)quinoline (CAS 1189107-42-3)
- tert-Butyl 7-bromo-3-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate (CAS 1160247-52-8)
- 3-Methyl-3-buten-1-ol (CAS 763-32-6)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
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