2-(Chloromethyl)-3-(difluoromethyl)-5-nitropyridine CAS 1803693-30-2
| CAS No. | 1803693-30-2 |
| Molecular Formula | C7H5ClF2N2O2 |
| Molecular Weight | 222.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 222.58 g/mol gives 2-(Chloromethyl)-3-(difluoromethyl)-5-nitropyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(Chloromethyl)-3-(difluoromethyl)-5-nitropyridine (CAS 1803693-30-2) is a high-purity analytical reference standard with the molecular formula C7H5ClF2N2O2 and a molecular weight of 222.58 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-(Chloromethyl)-3-(difluoromethyl)-5-nitropyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Chloromethyl)-3-(difluoromethyl)-5-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF2N2O2 |
| Molecular Weight | 222.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-4-(difluoromethyl)-3-nitropyridine (CAS 1806072-39-8)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-nitropyridine (CAS 1806777-37-6)
- 3-(Chloromethyl)-5-(trifluoromethyl)benzaldehyde (CAS 1393546-92-3)
- 3-(Chloromethyl)-6-(difluoromethyl)-4-methoxypyridin-2-amine (CAS 1804923-43-0)
- 6-(Chloromethyl)-4-(difluoromethyl)-3-methoxypyridin-2-amine (CAS 1804923-52-1)
- 5-(Chloromethyl)-6-(difluoromethyl)-3-methoxypyridin-2-amine (CAS 1805368-71-1)
- 3-(Chloromethyl)-5-(difluoromethyl)-6-methoxypyridin-2-amine (CAS 1805970-55-1)
- 5-(Chloromethyl)-4-(difluoromethyl)-3-methoxypyridin-2-amine (CAS 1806790-23-7)
Recommended Standards
- 2-Amino-6-chloro-4-(difluoromethyl)nicotinic acid (CAS 1803668-49-6)
- 4-Amino-6-chloro-3-(difluoromethyl)pyridine-2-carboxylic acid (CAS 1804451-66-8)
- 6-Amino-3-chloro-5-(difluoromethyl)picolinic acid (CAS 1803668-45-2)
- 4-Amino-6-chloro-5-(difluoromethyl)picolinic acid (CAS 1805008-61-0)
- Methyl 2-(difluoromethoxy)-5-methylbenzoate (CAS 639826-20-3)
- 2-(Aminomethyl)-1,3-benzodioxole (CAS 936-78-7)
- 1-(2-Diethylamino-ethyl)-5-oxo-pyrrolidine-3-carboxylic acid (CAS 876708-73-5)
- 4-(4-Chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-5-amine (CAS 1202029-56-8)
- 2-(((5-Carboxyfuran-2-yl)methyl)thio)succinic acid (CAS 91634-28-5)
- 2,4-Dibromo-3-fluorobenzyl alcohol (CAS 1806306-94-4)
- 2-Iodo-5-(morpholinosulfonyl)benzoic acid (CAS 926218-33-9)
- 3-Amino-4-(methylsulfanyl)butan-1-ol (CAS 1334146-75-6)
- 3-Cyclopropyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile (CAS 1153949-61-1)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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