2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethoxy)pyridine-4-sulfonyl chloride CAS 1804003-70-0

Description

2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethoxy)pyridine-4-sulfonyl chloride (CAS 1804003-70-0), molecular formula C8H6ClF5N2O3S and molecular weight 340.65 g/mol, is a CATO reference standard with documented purity and traceability.

2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethoxy)pyridine-4-sulfonyl chloride (C8H6ClF5N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethoxy)pyridine-4-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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