2-(Aminomethyl)-6-(difluoromethyl)-5-(trifluoromethoxy)pyridine-3-sulfonyl chloride CAS 1806759-69-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1806759-69-2
Molecular FormulaC8H6ClF5N2O3S
Molecular Weight340.65 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Aminomethyl)-6-(difluoromethyl)-5-(trifluoromethoxy)pyridine-3-sulfonyl chloride CAS 1806759-69-2 chemical structure

Description

2-(Aminomethyl)-6-(difluoromethyl)-5-(trifluoromethoxy)pyridine-3-sulfonyl chloride (C8H6ClF5N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

CATO supplies 2-(Aminomethyl)-6-(difluoromethyl)-5-(trifluoromethoxy)pyridine-3-sulfonyl chloride (CAS 1806759-69-2), a certified reference material (molecular formula C8H6ClF5N2O3S, MW 340.65 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Aminomethyl)-6-(difluoromethyl)-5-(trifluoromethoxy)pyridine-3-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H6ClF5N2O3S
Molecular Weight340.65 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms2
Sulfur Atoms1

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